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- NCIT_C106116 IAO_0000115 "A defucosylated, humanized IgG1 monoclonal antibody directed against the extracellular domain of the human CD70 molecule with potential antineoplastic activity. Upon administration, cusatuzumab selectively binds to, and neutralizes the activity of CD70, which may also induce an antibody-dependent cellular cytotoxicity (ADCC) response against CD70-expressing tumor cells. CD70, the ligand for the costimulatory receptor CD27 and a member of the tumor necrosis factor (TNF) family, is found on a number of solid and hematological tumors. Its overexpression may play an important role in evasion of immune surveillance." @default.
- NCIT_C106116 NCIT_A32 NCIT_C1909 @default.
- NCIT_C106116 NCIT_A7 NCIT_C104079 @default.
- NCIT_C106116 NCIT_NHC0 "C106116" @default.
- NCIT_C106116 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C106116 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C106116 NCIT_P107 "Cusatuzumab" @default.
- NCIT_C106116 NCIT_P108 "Cusatuzumab" @default.
- NCIT_C106116 NCIT_P208 "CL447355" @default.
- NCIT_C106116 NCIT_P210 "1864871-20-4" @default.
- NCIT_C106116 NCIT_P319 "RR5U4UFJ8L" @default.
- NCIT_C106116 NCIT_P322 "CTRP" @default.
- NCIT_C106116 NCIT_P322 "FDA" @default.
- NCIT_C106116 NCIT_P322 "GDC" @default.
- NCIT_C106116 NCIT_P329 "748589" @default.
- NCIT_C106116 NCIT_P330 "748589" @default.
- NCIT_C106116 NCIT_P375 "Cusatuzumab" @default.
- NCIT_C106116 NCIT_P399 "748589" @default.
- NCIT_C106116 NCIT_R124 NCIT_C17710 @default.
- NCIT_C106116 NCIT_R124 NCIT_C17828 @default.
- NCIT_C106116 NCIT_R124 NCIT_C18219 @default.
- NCIT_C106116 NCIT_R124 NCIT_C19986 @default.
- NCIT_C106116 NCIT_R124 NCIT_C40474 @default.
- NCIT_C106116 normalizedInformationContent "100" @default.
- NCIT_C106116 referenceCount "1" @default.
- NCIT_C106116 hasExactSynonym "ARGX-110" @default.
- NCIT_C106116 hasExactSynonym "Anti-CD70 Monoclonal Antibody ARGX-110" @default.
- NCIT_C106116 hasExactSynonym "CUSATUZUMAB" @default.
- NCIT_C106116 hasExactSynonym "Cusatuzumab" @default.
- NCIT_C106116 inSubset NCIT_C116977 @default.
- NCIT_C106116 inSubset NCIT_C116978 @default.
- NCIT_C106116 inSubset NCIT_C128784 @default.
- NCIT_C106116 inSubset NCIT_C157711 @default.
- NCIT_C106116 inSubset NCIT_C157712 @default.
- NCIT_C106116 inSubset NCIT_C176424 @default.
- NCIT_C106116 inSubset NCIT_C177537 @default.
- NCIT_C106116 inSubset NCIT_C63923 @default.
- NCIT_C106116 type Class @default.
- NCIT_C106116 isDefinedBy ncit.owl @default.
- NCIT_C106116 label "Cusatuzumab" @default.
- NCIT_C106116 subClassOf NCIT_C106116 @default.
- NCIT_C106116 subClassOf NCIT_C129821 @default.
- NCIT_C106116 subClassOf NCIT_C129822 @default.
- NCIT_C106116 subClassOf NCIT_C163758 @default.
- NCIT_C106116 subClassOf NCIT_C1908 @default.
- NCIT_C106116 subClassOf NCIT_C1909 @default.
- NCIT_C106116 subClassOf NCIT_C192643 @default.
- NCIT_C106116 subClassOf NCIT_C200042 @default.
- NCIT_C106116 subClassOf NCIT_C20401 @default.
- NCIT_C106116 subClassOf NCIT_C274 @default.
- NCIT_C106116 subClassOf NCIT_C307 @default.
- NCIT_C106116 subClassOf NCIT_C308 @default.