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- NCIT_C106262 IAO_0000115 "An immunoglobulin G1 (IgG1) humanized monoclonal antibody directed against human hepatocyte growth factor receptor (HGFR or c-Met), with potential antineoplastic activity. Telisotuzumab binds to c-Met, thereby preventing both c-Met binding to its ligand, HGF and the subsequent activation of the HGF/c-Met signaling pathway. This may cause cell death in c-Met-expressing tumor cells. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis." @default.
- NCIT_C106262 NCIT_A32 NCIT_C1909 @default.
- NCIT_C106262 NCIT_A7 NCIT_C18186 @default.
- NCIT_C106262 NCIT_NHC0 "C106262" @default.
- NCIT_C106262 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C106262 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C106262 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C106262 NCIT_P107 "Telisotuzumab" @default.
- NCIT_C106262 NCIT_P108 "Telisotuzumab" @default.
- NCIT_C106262 NCIT_P208 "CL433934" @default.
- NCIT_C106262 NCIT_P210 "1781223-80-0" @default.
- NCIT_C106262 NCIT_P319 "R15ZW356HN" @default.
- NCIT_C106262 NCIT_P322 "CTRP" @default.
- NCIT_C106262 NCIT_P322 "FDA" @default.
- NCIT_C106262 NCIT_P322 "GDC" @default.
- NCIT_C106262 NCIT_P329 "717765" @default.
- NCIT_C106262 NCIT_P330 "717765" @default.
- NCIT_C106262 NCIT_P375 "Anti-c-Met Monoclonal Antibody ABT-700" @default.
- NCIT_C106262 NCIT_P375 "Telisotuzumab" @default.
- NCIT_C106262 NCIT_P399 "717765" @default.
- NCIT_C106262 NCIT_R124 NCIT_C17710 @default.
- NCIT_C106262 NCIT_R124 NCIT_C17828 @default.
- NCIT_C106262 NCIT_R124 NCIT_C18219 @default.
- NCIT_C106262 NCIT_R124 NCIT_C19986 @default.
- NCIT_C106262 NCIT_R124 NCIT_C40474 @default.
- NCIT_C106262 normalizedInformationContent "100" @default.
- NCIT_C106262 referenceCount "1" @default.
- NCIT_C106262 hasExactSynonym "ABT-700" @default.
- NCIT_C106262 hasExactSynonym "Anti-c-Met Monoclonal Antibody ABT-700" @default.
- NCIT_C106262 hasExactSynonym "TELISOTUZUMAB" @default.
- NCIT_C106262 hasExactSynonym "Telisotuzumab" @default.
- NCIT_C106262 inSubset NCIT_C116977 @default.
- NCIT_C106262 inSubset NCIT_C116978 @default.
- NCIT_C106262 inSubset NCIT_C128784 @default.
- NCIT_C106262 inSubset NCIT_C157711 @default.
- NCIT_C106262 inSubset NCIT_C157712 @default.
- NCIT_C106262 inSubset NCIT_C176424 @default.
- NCIT_C106262 inSubset NCIT_C177537 @default.
- NCIT_C106262 inSubset NCIT_C63923 @default.
- NCIT_C106262 type Class @default.
- NCIT_C106262 isDefinedBy ncit.owl @default.
- NCIT_C106262 label "Telisotuzumab" @default.
- NCIT_C106262 subClassOf NCIT_C106262 @default.
- NCIT_C106262 subClassOf NCIT_C129821 @default.
- NCIT_C106262 subClassOf NCIT_C129822 @default.
- NCIT_C106262 subClassOf NCIT_C163758 @default.
- NCIT_C106262 subClassOf NCIT_C164000 @default.
- NCIT_C106262 subClassOf NCIT_C164001 @default.
- NCIT_C106262 subClassOf NCIT_C1908 @default.
- NCIT_C106262 subClassOf NCIT_C1909 @default.
- NCIT_C106262 subClassOf NCIT_C20401 @default.
- NCIT_C106262 subClassOf NCIT_C274 @default.
- NCIT_C106262 subClassOf NCIT_C307 @default.
- NCIT_C106262 subClassOf NCIT_C308 @default.