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- NCIT_C106371 IAO_0000115 "A proprietary water- and lipid-soluble polymer-based nutritional supplement composed of a complex mixture of alpha-lipoic acid bound to palladium (Palladium Lipoic Acid Complex (PdLA)) and other minerals, vitamins and amino acids, including vitamins B1, B2 and B12, formylmethionine, acetyl cysteine, and trace amounts of molybdinum, rhodium, and ruthenium, with potential anti-oxidant and cytoprotective activities. Upon oral administration, the alpha-lipoic acid-palladium/vitamin/mineral supplement acts as a free radical scavenger, crosses the cell membrane and is able to transfer electrons from fatty acids to DNA via the electron transport chain in mitochondria, which protects against DNA damage. This could protect non-cancerous cells from the oxidative damage caused by radiation and chemotherapy. In addition, in the hypoxic conditions found within tumors, the excess electrons can generate free radicals within mitochondria and could induce both cytochrome c release and apoptosis." @default.
- NCIT_C106371 NCIT_NHC0 "C106371" @default.
- NCIT_C106371 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C106371 NCIT_P108 "Alpha-lipoic Acid-Palladium/Vitamin/Mineral Supplement" @default.
- NCIT_C106371 NCIT_P208 "CL447737" @default.
- NCIT_C106371 NCIT_P329 "749638" @default.
- NCIT_C106371 NCIT_P330 "749638" @default.
- NCIT_C106371 NCIT_P399 "749638" @default.
- NCIT_C106371 normalizedInformationContent "100" @default.
- NCIT_C106371 referenceCount "1" @default.
- NCIT_C106371 hasExactSynonym "Alpha-lipoic Acid-Palladium/Vitamin/Mineral Supplement" @default.
- NCIT_C106371 hasExactSynonym "LAPd" @default.
- NCIT_C106371 hasExactSynonym "Palladium Lipoic Complex" @default.
- NCIT_C106371 hasExactSynonym "PolyMVA" @default.
- NCIT_C106371 inSubset NCIT_C128784 @default.
- NCIT_C106371 inSubset NCIT_C176424 @default.
- NCIT_C106371 type Class @default.
- NCIT_C106371 isDefinedBy ncit.owl @default.
- NCIT_C106371 label "Alpha-lipoic Acid-Palladium/Vitamin/Mineral Supplement" @default.
- NCIT_C106371 subClassOf NCIT_C106371 @default.
- NCIT_C106371 subClassOf NCIT_C1505 @default.
- NCIT_C106371 subClassOf NCIT_C1908 @default.