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- NCIT_C1066 IAO_0000115 "A semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin." @default.
- NCIT_C1066 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1066 NCIT_NHC0 "C1066" @default.
- NCIT_C1066 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1066 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1066 NCIT_P108 "Detorubicin" @default.
- NCIT_C1066 NCIT_P175 "292652" @default.
- NCIT_C1066 NCIT_P207 "C0057578" @default.
- NCIT_C1066 NCIT_P210 "66211-92-5" @default.
- NCIT_C1066 NCIT_P319 "822EC3XEJZ" @default.
- NCIT_C1066 NCIT_P322 "FDA" @default.
- NCIT_C1066 NCIT_P322 "GDC" @default.
- NCIT_C1066 NCIT_P329 "39213" @default.
- NCIT_C1066 NCIT_P330 "39213" @default.
- NCIT_C1066 NCIT_P350 "C33H39NO14" @default.
- NCIT_C1066 NCIT_P366 "Detorubicin" @default.
- NCIT_C1066 NCIT_P375 "Detorubicin" @default.
- NCIT_C1066 NCIT_P399 "39213" @default.
- NCIT_C1066 normalizedInformationContent "100" @default.
- NCIT_C1066 referenceCount "1" @default.
- NCIT_C1066 hasExactSynonym "14-Diethoxyacetoxydaunorubicin" @default.
- NCIT_C1066 hasExactSynonym "DETORUBICIN" @default.
- NCIT_C1066 hasExactSynonym "Detorubicin" @default.
- NCIT_C1066 hasExactSynonym "Diethoxy-,2-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl)-2-oxoethyl ester,(2S-cis) Acetic Acid" @default.
- NCIT_C1066 inSubset NCIT_C128784 @default.
- NCIT_C1066 inSubset NCIT_C157711 @default.
- NCIT_C1066 inSubset NCIT_C157712 @default.
- NCIT_C1066 inSubset NCIT_C176424 @default.
- NCIT_C1066 inSubset NCIT_C177537 @default.
- NCIT_C1066 inSubset NCIT_C63923 @default.
- NCIT_C1066 type Class @default.
- NCIT_C1066 isDefinedBy ncit.owl @default.
- NCIT_C1066 label "Detorubicin" @default.
- NCIT_C1066 subClassOf NCIT_C1066 @default.
- NCIT_C1066 subClassOf NCIT_C129824 @default.
- NCIT_C1066 subClassOf NCIT_C129825 @default.
- NCIT_C1066 subClassOf NCIT_C1594 @default.
- NCIT_C1066 subClassOf NCIT_C1748 @default.
- NCIT_C1066 subClassOf NCIT_C186664 @default.
- NCIT_C1066 subClassOf NCIT_C1908 @default.
- NCIT_C1066 subClassOf NCIT_C1909 @default.
- NCIT_C1066 subClassOf NCIT_C1968 @default.
- NCIT_C1066 subClassOf NCIT_C2115 @default.
- NCIT_C1066 subClassOf NCIT_C2161 @default.
- NCIT_C1066 subClassOf NCIT_C2189 @default.
- NCIT_C1066 subClassOf NCIT_C259 @default.
- NCIT_C1066 subClassOf NCIT_C274 @default.
- NCIT_C1066 subClassOf NCIT_C2842 @default.
- NCIT_C1066 subClassOf NCIT_C471 @default.