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- NCIT_C107167 IAO_0000115 "A vaccine composed of a phosphorylated peptide from the tumor associated antigen insulin receptor substrate-2 (IRS2) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pIRS2 phosphopeptide-tetanus peptide vaccine, the pIRS2 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against phosphopeptide-containing tumor cells. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response which may help stimulate an immune response against the pIRS2-expressing melanoma tumor cells. IRS2 is upregulated in a variety of cancer cells." @default.
- NCIT_C107167 NCIT_NHC0 "C107167" @default.
- NCIT_C107167 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C107167 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C107167 NCIT_P108 "pIRS2 Phosphopeptide-tetanus Peptide Vaccine" @default.
- NCIT_C107167 NCIT_P208 "CL449427" @default.
- NCIT_C107167 NCIT_P329 "750409" @default.
- NCIT_C107167 NCIT_P330 "750409" @default.
- NCIT_C107167 NCIT_P399 "750409" @default.
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- NCIT_C107167 normalizedInformationContent "100" @default.
- NCIT_C107167 referenceCount "1" @default.
- NCIT_C107167 hasExactSynonym "pIRS2 Phosphopeptide-tetanus Peptide Vaccine" @default.
- NCIT_C107167 hasExactSynonym "pIRS2-phosphopeptide Plus Tet Vaccine" @default.
- NCIT_C107167 inSubset NCIT_C128784 @default.
- NCIT_C107167 inSubset NCIT_C176424 @default.
- NCIT_C107167 type Class @default.
- NCIT_C107167 isDefinedBy ncit.owl @default.
- NCIT_C107167 label "pIRS2 Phosphopeptide-tetanus Peptide Vaccine" @default.
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