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- NCIT_C107168 IAO_0000115 "A vaccine composed of phosphorylated peptides from the tumor associated antigens breast cancer anti-estrogen resistance-3 (BCAR3) and insulin receptor substrate-2 (IRS2) and a tetanus-derived peptide, with potential immunomodulating and antineoplastic activities. Upon administration of pBCAR3/pIRS2 phosphopeptide-tetanus peptide vaccine, the pBCAR3/pIRS2 phosphopeptide may stimulate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against tumor cells expressing either phosphopeptide. The tetanus peptide serves as an immunoadjuvant and induces a helper T-cell response which may help stimulate an immune response against pBCAR3 and pIRS2-expressing melanoma tumor cells. BCAR3 and IRS2 are upregulated in a variety of cancer cells." @default.
- NCIT_C107168 NCIT_NHC0 "C107168" @default.
- NCIT_C107168 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C107168 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C107168 NCIT_P108 "pBCAR3/pIRS2-Phosphopeptide-tetanus Peptide Vaccine" @default.
- NCIT_C107168 NCIT_P208 "CL449428" @default.
- NCIT_C107168 NCIT_P329 "750410" @default.
- NCIT_C107168 NCIT_P330 "750410" @default.
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- NCIT_C107168 normalizedInformationContent "100" @default.
- NCIT_C107168 referenceCount "1" @default.
- NCIT_C107168 hasExactSynonym "2-MpP Phosphopeptide-tetanus Peptide Vaccine" @default.
- NCIT_C107168 hasExactSynonym "pBCAR3/pIRS2-Phosphopeptide-tetanus Peptide Vaccine" @default.
- NCIT_C107168 inSubset NCIT_C128784 @default.
- NCIT_C107168 inSubset NCIT_C176424 @default.
- NCIT_C107168 type Class @default.
- NCIT_C107168 isDefinedBy ncit.owl @default.
- NCIT_C107168 label "pBCAR3/pIRS2-Phosphopeptide-tetanus Peptide Vaccine" @default.
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