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- NCIT_C107555 IAO_0000115 "An active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in cancer cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway." @default.
- NCIT_C107555 NCIT_A32 NCIT_C1909 @default.
- NCIT_C107555 NCIT_NHC0 "C107555" @default.
- NCIT_C107555 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C107555 NCIT_P107 "Bufalin" @default.
- NCIT_C107555 NCIT_P108 "Bufalin" @default.
- NCIT_C107555 NCIT_P207 "C0054205" @default.
- NCIT_C107555 NCIT_P210 "465-21-4" @default.
- NCIT_C107555 NCIT_P319 "U549S98QLW" @default.
- NCIT_C107555 NCIT_P322 "CTRP" @default.
- NCIT_C107555 NCIT_P322 "FDA" @default.
- NCIT_C107555 NCIT_P322 "GDC" @default.
- NCIT_C107555 NCIT_P375 "Bufalin" @default.
- NCIT_C107555 normalizedInformationContent "100" @default.
- NCIT_C107555 referenceCount "1" @default.
- NCIT_C107555 hasExactSynonym "3,14-Dihydroxy-Bufa-20,22-Dienolide" @default.
- NCIT_C107555 hasExactSynonym "3-Beta,14-Dihydroxy-5-Beta-Bufa-20,22-Dienolide" @default.
- NCIT_C107555 hasExactSynonym "3beta,14beta-Dihydroxy-5beta-Bufa-20,22-Dienolide" @default.
- NCIT_C107555 hasExactSynonym "5-Beta-Bufa-20,22-Dienolide, 3-Beta,14-Dihydroxy-" @default.
- NCIT_C107555 hasExactSynonym "5beta-Bufa-20,22-Dienolide, 3beta,14-Dihydroxy- (8CI)" @default.
- NCIT_C107555 hasExactSynonym "BUFALIN" @default.
- NCIT_C107555 hasExactSynonym "Bufa-20,22-Dienolide, 3,14-Dihydroxy-, (3-Beta,5-Beta)- (9CI)" @default.
- NCIT_C107555 hasExactSynonym "Bufa-20,22-Dienolide, 3,14-Dihydroxy-, (3beta,5beta)- (9CI)" @default.
- NCIT_C107555 hasExactSynonym "Bufalin" @default.
- NCIT_C107555 inSubset NCIT_C116977 @default.
- NCIT_C107555 inSubset NCIT_C128784 @default.
- NCIT_C107555 inSubset NCIT_C142799 @default.
- NCIT_C107555 inSubset NCIT_C157711 @default.
- NCIT_C107555 inSubset NCIT_C157712 @default.
- NCIT_C107555 inSubset NCIT_C177537 @default.
- NCIT_C107555 inSubset NCIT_C63923 @default.
- NCIT_C107555 type Class @default.
- NCIT_C107555 isDefinedBy ncit.owl @default.
- NCIT_C107555 label "Bufalin" @default.
- NCIT_C107555 subClassOf NCIT_C107555 @default.
- NCIT_C107555 subClassOf NCIT_C1908 @default.
- NCIT_C107555 subClassOf NCIT_C1909 @default.
- NCIT_C107555 subClassOf NCIT_C471 @default.