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- NCIT_C1093 IAO_0000115 "A phosphate salt of a semisynthetic derivative of podophyllotoxin. Etoposide binds to the enzyme topoisomerase II, inducing double-strand DNA breaks, inhibiting DNA repair, and resulting in decreased DNA synthesis and tumor cell proliferation. Cells in the S and G2 phases of the cell cycle are most sensitive to this agent. (NCI04)" @default.
- NCIT_C1093 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1093 NCIT_A33 NCIT_C274 @default.
- NCIT_C1093 NCIT_A7 NCIT_C18434 @default.
- NCIT_C1093 NCIT_NHC0 "C1093" @default.
- NCIT_C1093 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1093 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1093 NCIT_P107 "Etoposide Phosphate" @default.
- NCIT_C1093 NCIT_P108 "Etoposide Phosphate" @default.
- NCIT_C1093 NCIT_P207 "C0059874" @default.
- NCIT_C1093 NCIT_P210 "117091-64-2" @default.
- NCIT_C1093 NCIT_P302 "Acute leukemia; Adrenal cortical cancer; Brain cancer; Chronic lymphocytic leukemia; Choriocarcinoma; Esophageal cancer; Ewings sarcoma; Gastric cancer; Germ cell cancer; Gestational trophoblastic neoplasms" @default.
- NCIT_C1093 NCIT_P302 "Hepatocellular cancer; Hodgkins disease; Hypereosinophilic syndrome; Kaposis sarcoma; Testicular cancer; Thymoma; Thyroid cancer; Uterine cancer; Wilms tumor" @default.
- NCIT_C1093 NCIT_P302 "Langerhans cell histiocytosis; Mobilization of peripheral-blood progenitor cells; Multiple myeloma; Neuroblastoma; Non-small lung cancer; Osteogenic sarcoma; Ovarian cancer; Retinoblastoma; Small cell lung cancer; Soft tissue sarcomas" @default.
- NCIT_C1093 NCIT_P319 "528XYJ8L1N" @default.
- NCIT_C1093 NCIT_P322 "CTRP" @default.
- NCIT_C1093 NCIT_P322 "FDA" @default.
- NCIT_C1093 NCIT_P322 "GDC" @default.
- NCIT_C1093 NCIT_P322 "PCDC" @default.
- NCIT_C1093 NCIT_P325 "A drug used to treat testicular and small cell lung cancers. It is also being studied in the treatment of several other types of cancer. Etopophos blocks certain enzymes needed for cell division and DNA repair, and it may kill cancer cells. It is a type of podophyllotoxin derivative and a type of topoisomerase inhibitor." @default.
- NCIT_C1093 NCIT_P329 "42801" @default.
- NCIT_C1093 NCIT_P330 "42801" @default.
- NCIT_C1093 NCIT_P350 "C29H33O16P" @default.
- NCIT_C1093 NCIT_P366 "Etoposide_Phosphate" @default.
- NCIT_C1093 NCIT_P375 "Etoposide Phosphate" @default.
- NCIT_C1093 NCIT_P399 "42801" @default.
- NCIT_C1093 normalizedInformationContent "85.460608731874885" @default.
- NCIT_C1093 referenceCount "9" @default.
- NCIT_C1093 hasExactSynonym "ETOPOSIDE PHOSPHATE" @default.
- NCIT_C1093 hasExactSynonym "Etopophos" @default.
- NCIT_C1093 hasExactSynonym "Etoposide Phosphate" @default.
- NCIT_C1093 hasExactSynonym "etoposide phosphate" @default.
- NCIT_C1093 inSubset NCIT_C116977 @default.
- NCIT_C1093 inSubset NCIT_C116978 @default.
- NCIT_C1093 inSubset NCIT_C128784 @default.
- NCIT_C1093 inSubset NCIT_C157711 @default.
- NCIT_C1093 inSubset NCIT_C157712 @default.
- NCIT_C1093 inSubset NCIT_C176424 @default.
- NCIT_C1093 inSubset NCIT_C177383 @default.
- NCIT_C1093 inSubset NCIT_C177406 @default.
- NCIT_C1093 inSubset NCIT_C177537 @default.
- NCIT_C1093 inSubset NCIT_C186327 @default.
- NCIT_C1093 inSubset NCIT_C186328 @default.
- NCIT_C1093 inSubset NCIT_C186341 @default.
- NCIT_C1093 inSubset NCIT_C63923 @default.
- NCIT_C1093 type Class @default.
- NCIT_C1093 isDefinedBy ncit.owl @default.
- NCIT_C1093 label "Etoposide Phosphate" @default.
- NCIT_C1093 subClassOf NCIT_C1093 @default.
- NCIT_C1093 subClassOf NCIT_C129824 @default.
- NCIT_C1093 subClassOf NCIT_C129825 @default.
- NCIT_C1093 subClassOf NCIT_C1331 @default.
- NCIT_C1093 subClassOf NCIT_C1748 @default.
- NCIT_C1093 subClassOf NCIT_C1907 @default.
- NCIT_C1093 subClassOf NCIT_C1908 @default.
- NCIT_C1093 subClassOf NCIT_C1909 @default.
- NCIT_C1093 subClassOf NCIT_C1931 @default.
- NCIT_C1093 subClassOf NCIT_C1968 @default.
- NCIT_C1093 subClassOf NCIT_C2189 @default.
- NCIT_C1093 subClassOf NCIT_C274 @default.
- NCIT_C1093 subClassOf NCIT_C471 @default.