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- NCIT_C111764 IAO_0000115 "An orally bioavailable ditosilate salt form of selatinib, an analog of the quinazoline lapatinib and dual inhibitor of epidermal growth factor receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (ErbB-2 or HER-2), with potential antineoplastic activity. Upon administration, selatinib reversibly blocks phosphorylation of both EGFR and ErbB2, thereby suppressing tumor growth in EGFR/ErbB-2-overexpressing tumor cells. The tyrosine kinases EGFR and ErbB2 have been implicated in the growth of various tumor types." @default.
- NCIT_C111764 NCIT_A32 NCIT_C1909 @default.
- NCIT_C111764 NCIT_A7 NCIT_C17068 @default.
- NCIT_C111764 NCIT_NHC0 "C111764" @default.
- NCIT_C111764 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C111764 NCIT_P108 "Selatinib Ditosilate" @default.
- NCIT_C111764 NCIT_P208 "CL454151" @default.
- NCIT_C111764 NCIT_P210 "1452886-38-2" @default.
- NCIT_C111764 NCIT_P319 "6Q2E32HVE7" @default.
- NCIT_C111764 NCIT_P322 "FDA" @default.
- NCIT_C111764 NCIT_P322 "GDC" @default.
- NCIT_C111764 NCIT_P329 "753197" @default.
- NCIT_C111764 NCIT_P330 "753197" @default.
- NCIT_C111764 NCIT_P375 "Selatinib Ditosilate" @default.
- NCIT_C111764 NCIT_P399 "753197" @default.
- NCIT_C111764 normalizedInformationContent "100" @default.
- NCIT_C111764 referenceCount "1" @default.
- NCIT_C111764 hasExactSynonym "SELATINIB DITOSILATE" @default.
- NCIT_C111764 hasExactSynonym "Selatinib Ditosilate" @default.
- NCIT_C111764 inSubset NCIT_C128784 @default.
- NCIT_C111764 inSubset NCIT_C157711 @default.
- NCIT_C111764 inSubset NCIT_C157712 @default.
- NCIT_C111764 inSubset NCIT_C176424 @default.
- NCIT_C111764 inSubset NCIT_C177537 @default.
- NCIT_C111764 inSubset NCIT_C63923 @default.
- NCIT_C111764 type Class @default.
- NCIT_C111764 isDefinedBy ncit.owl @default.
- NCIT_C111764 label "Selatinib Ditosilate" @default.
- NCIT_C111764 subClassOf NCIT_C111764 @default.
- NCIT_C111764 subClassOf NCIT_C129824 @default.
- NCIT_C111764 subClassOf NCIT_C129825 @default.
- NCIT_C111764 subClassOf NCIT_C1404 @default.
- NCIT_C111764 subClassOf NCIT_C163758 @default.
- NCIT_C111764 subClassOf NCIT_C163952 @default.
- NCIT_C111764 subClassOf NCIT_C1908 @default.
- NCIT_C111764 subClassOf NCIT_C1909 @default.
- NCIT_C111764 subClassOf NCIT_C1967 @default.
- NCIT_C111764 subClassOf NCIT_C2167 @default.
- NCIT_C111764 subClassOf NCIT_C2189 @default.
- NCIT_C111764 subClassOf NCIT_C274 @default.
- NCIT_C111764 subClassOf NCIT_C471 @default.