Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C111998> ?p ?o ?g. }
Showing items 1 to 36 of
36
with 100 items per page.
- NCIT_C111998 IAO_0000115 "A live-attenuated, double-deleted strain of the Gram-positive bacterium Listeria monocytogenes (Lm) encoding a mutant form of the tumor associated antigens, epidermal growth factor receptor (EGFRvIII) and the cancer/testis antigen NY-ESO-1, with potential immunostimulatory and antineoplastic activities. Upon intravenous administration, live-attenuated Listeria monocytogenes encoding EGFRvIII-NY-ESO-1 vaccine targets dendritic cells and expresses EGFRvIII and NY-ESO-1. This promotes both a potent innate immune response and an adaptive immune response involving the recruitment and activation of T lymphocytes against EGFRvIII and NY-ESO-1-expressing tumor cells, which results in tumor cell lysis." @default.
- NCIT_C111998 NCIT_A32 NCIT_C1909 @default.
- NCIT_C111998 NCIT_NHC0 "C111998" @default.
- NCIT_C111998 NCIT_P106 "Bacterium" @default.
- NCIT_C111998 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C111998 NCIT_P108 "Live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 Vaccine ADU-623" @default.
- NCIT_C111998 NCIT_P208 "CL454287" @default.
- NCIT_C111998 NCIT_P322 "GDC" @default.
- NCIT_C111998 NCIT_P329 "754227" @default.
- NCIT_C111998 NCIT_P330 "754227" @default.
- NCIT_C111998 NCIT_P375 "Live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 Vaccine ADU-623" @default.
- NCIT_C111998 NCIT_P399 "754227" @default.
- NCIT_C111998 normalizedInformationContent "100" @default.
- NCIT_C111998 referenceCount "1" @default.
- NCIT_C111998 hasExactSynonym "ADU-623" @default.
- NCIT_C111998 hasExactSynonym "Live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 Vaccine ADU-623" @default.
- NCIT_C111998 inSubset NCIT_C128784 @default.
- NCIT_C111998 inSubset NCIT_C157711 @default.
- NCIT_C111998 inSubset NCIT_C157712 @default.
- NCIT_C111998 inSubset NCIT_C176424 @default.
- NCIT_C111998 inSubset NCIT_C177537 @default.
- NCIT_C111998 type Class @default.
- NCIT_C111998 isDefinedBy ncit.owl @default.
- NCIT_C111998 label "Live-attenuated Listeria monocytogenes-encoding EGFRvIII-NY-ESO-1 Vaccine ADU-623" @default.
- NCIT_C111998 subClassOf NCIT_C111998 @default.
- NCIT_C111998 subClassOf NCIT_C129820 @default.
- NCIT_C111998 subClassOf NCIT_C1663 @default.
- NCIT_C111998 subClassOf NCIT_C1908 @default.
- NCIT_C111998 subClassOf NCIT_C1909 @default.
- NCIT_C111998 subClassOf NCIT_C274 @default.
- NCIT_C111998 subClassOf NCIT_C307 @default.
- NCIT_C111998 subClassOf NCIT_C308 @default.
- NCIT_C111998 subClassOf NCIT_C62761 @default.
- NCIT_C111998 subClassOf NCIT_C923 @default.
- NCIT_C111998 subClassOf NCIT_C96390 @default.
- NCIT_C111998 subClassOf NCIT_C97116 @default.