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- NCIT_C112499 IAO_0000115 "An immunoconjugate comprised of the recombinant chimeric monoclonal antibody cetuximab conjugated to the N-hydroxysuccinamide (NHS) ester form of the near-infrared (NIR) fluorescent dye IRDye 800CW (cetuximab-IRDye 800) with potential imaging use. The antibody moiety of cetuximab-IRDye 800 binds to the extracellular domain of the epidermal growth factor receptor (EGFR). Upon binding, IRDye 800 may be detected using NIR imaging, which facilitates the visualization and quantification of EGFR-expressing tumor cells. EGFR is a receptor tyrosine kinase that may be overexpressed on the cell surfaces of various tumor types." @default.
- NCIT_C112499 NCIT_A7 NCIT_C17068 @default.
- NCIT_C112499 NCIT_NHC0 "C112499" @default.
- NCIT_C112499 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C112499 NCIT_P107 "Cetuximab-IRDye 800CW" @default.
- NCIT_C112499 NCIT_P108 "Cetuximab-IRDye 800CW" @default.
- NCIT_C112499 NCIT_P208 "CL454673" @default.
- NCIT_C112499 NCIT_P322 "CTRP" @default.
- NCIT_C112499 NCIT_P329 "755023" @default.
- NCIT_C112499 NCIT_P330 "755023" @default.
- NCIT_C112499 NCIT_P399 "755023" @default.
- NCIT_C112499 normalizedInformationContent "100" @default.
- NCIT_C112499 referenceCount "1" @default.
- NCIT_C112499 hasExactSynonym "Cetuximab-IRDye 800" @default.
- NCIT_C112499 hasExactSynonym "Cetuximab-IRDye 800CW" @default.
- NCIT_C112499 hasExactSynonym "Cetuximab-IRDye800" @default.
- NCIT_C112499 hasExactSynonym "Cetuximab-IRDye800CW" @default.
- NCIT_C112499 inSubset NCIT_C116977 @default.
- NCIT_C112499 inSubset NCIT_C116978 @default.
- NCIT_C112499 inSubset NCIT_C176424 @default.
- NCIT_C112499 type Class @default.
- NCIT_C112499 isDefinedBy ncit.owl @default.
- NCIT_C112499 label "Cetuximab-IRDye 800CW" @default.
- NCIT_C112499 subClassOf NCIT_C112499 @default.
- NCIT_C112499 subClassOf NCIT_C1512 @default.
- NCIT_C112499 subClassOf NCIT_C1908 @default.
- NCIT_C112499 subClassOf NCIT_C1909 @default.
- NCIT_C112499 subClassOf NCIT_C307 @default.
- NCIT_C112499 subClassOf NCIT_C308 @default.