Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C113498> ?p ?o ?g. }
Showing items 1 to 41 of
41
with 100 items per page.
- NCIT_C113498 IAO_0000115 "A ribonucleotide analog of adenosine monophosphate that is an intermediate in the synthesis of inosine monophosphate with potential cardioprotective activity. During myocardial ischemia, AICA-ribotide activates AMP-dependent protein kinase (AMPK), inhibits adenosine deaminase (ADA) and causes increased synthesis of both adenosine and adenosine triphosphate (ATP). These activities prevent calcium overload, increase AMPK-dependent glucose uptake and improve blood flow to the heart. AMPK, a protein kinase complex, regulates several cellular systems including the uptake of glucose, the beta-oxidation of fatty acids, protein synthesis, and the biogenesis of both glucose transporter 4 (GLUT4) and mitochondria. ADA is a key enzyme involved in purine metabolism." @default.
- NCIT_C113498 NCIT_NHC0 "C113498" @default.
- NCIT_C113498 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C113498 NCIT_P107 "AICA-Ribotide" @default.
- NCIT_C113498 NCIT_P108 "AICA-Ribotide" @default.
- NCIT_C113498 NCIT_P207 "C0051028" @default.
- NCIT_C113498 NCIT_P210 "3031-94-5" @default.
- NCIT_C113498 NCIT_P322 "CTRP" @default.
- NCIT_C113498 NCIT_P368 "CHEBI:18406" @default.
- NCIT_C113498 normalizedInformationContent "100" @default.
- NCIT_C113498 referenceCount "1" @default.
- NCIT_C113498 hasExactSynonym "1-(5'-Phosphoribosyl)-5-Amino-4-Imidazolecarboxamide" @default.
- NCIT_C113498 hasExactSynonym "1H-Imidazole-4-Carboxamide, 5-Amino-1-(5-O-Phosphono-Beta-D-Ribofuranosyl)- (9CI)" @default.
- NCIT_C113498 hasExactSynonym "5'-Phospho-Ribosyl-5-Amino-4-Imidazole Carboxamide" @default.
- NCIT_C113498 hasExactSynonym "5'-Phosphoribosyl-5-Amino-4-Imidazolecarboxamide" @default.
- NCIT_C113498 hasExactSynonym "5-Amino-1-(5-O-Phosphono-Beta-D-Ribofuranosyl)-1H-Imidazole-4-Carboxamide" @default.
- NCIT_C113498 hasExactSynonym "5-Amino-1-(5-Phospho-D-Ribosyl)Imidazole-4-Carboxamide" @default.
- NCIT_C113498 hasExactSynonym "5-Amino-4-Imidazole Carboxamide Ribonucleotide" @default.
- NCIT_C113498 hasExactSynonym "5-Amino-4-Imidazolecarboxamide Ribonucleoside 5'-Monophosphate" @default.
- NCIT_C113498 hasExactSynonym "5-Amino-4-Imidazolecarboxamide Ribotide" @default.
- NCIT_C113498 hasExactSynonym "5-Aminoimidazole-4-Carboxamide Ribonucleotide" @default.
- NCIT_C113498 hasExactSynonym "5-Phosphoribosyl-4-Carbamoyl-5-Aminoimidazole" @default.
- NCIT_C113498 hasExactSynonym "AICA Ribonucleotide" @default.
- NCIT_C113498 hasExactSynonym "AICA Ribotide" @default.
- NCIT_C113498 hasExactSynonym "AICA-Ribotide" @default.
- NCIT_C113498 hasExactSynonym "AICAR" @default.
- NCIT_C113498 hasExactSynonym "Aminoimidazole Carboxamide Ribonucleotide" @default.
- NCIT_C113498 hasExactSynonym "Imidazole-4-Carboxamide, 5-Amino-1-Beta-D-Ribofuranosyl-, 5'-(Dihydrogen Phosphate) (8CI)" @default.
- NCIT_C113498 hasExactSynonym "ZMP" @default.
- NCIT_C113498 hasExactSynonym "[(2R,3S,4R,5R)-5-(4-Carbamoyl-5-Aminoimidazol-1-yl)-3,4-Dihydroxyoxolan-2-yl]Methyl Dihydrogen Phosphate" @default.
- NCIT_C113498 inSubset NCIT_C116977 @default.
- NCIT_C113498 inSubset NCIT_C142799 @default.
- NCIT_C113498 type Class @default.
- NCIT_C113498 isDefinedBy ncit.owl @default.
- NCIT_C113498 label "AICA-Ribotide" @default.
- NCIT_C113498 subClassOf NCIT_C113498 @default.
- NCIT_C113498 subClassOf NCIT_C1908 @default.
- NCIT_C113498 subClassOf NCIT_C1913 @default.
- NCIT_C113498 subClassOf NCIT_C708 @default.
- NCIT_C113498 subClassOf NCIT_C709 @default.
- NCIT_C113498 subClassOf NCIT_C718 @default.