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- NCIT_C1135 IAO_0000115 "A naturally occurring, orally available cleavage product of the glucosinolate glucobrassicanin, a natural compound present in a wide variety of plant food substances including members of the family Cruciferae with antioxidant and potential chemopreventive properties. Indole-3-carbinol scavenges free radicals and induces various hepatic cytochrome P450 monooxygenases. Specifically, this agent induces the hepatic monooxygenase cytochrome P4501A1 (CYP1A1), resulting in increased 2-hydroxylation of estrogens and increased production of the chemoprotective estrogen 2-hydroxyestrone." @default.
- NCIT_C1135 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1135 NCIT_NHC0 "C1135" @default.
- NCIT_C1135 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1135 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1135 NCIT_P107 "Indole-3-Carbinol" @default.
- NCIT_C1135 NCIT_P108 "Indole-3-Carbinol" @default.
- NCIT_C1135 NCIT_P207 "C0063491" @default.
- NCIT_C1135 NCIT_P210 "700-06-1" @default.
- NCIT_C1135 NCIT_P319 "C11E72455F" @default.
- NCIT_C1135 NCIT_P322 "CRCH" @default.
- NCIT_C1135 NCIT_P322 "CTRP" @default.
- NCIT_C1135 NCIT_P322 "FDA" @default.
- NCIT_C1135 NCIT_P322 "GDC" @default.
- NCIT_C1135 NCIT_P325 "A substance that is being studied as a cancer prevention drug. It is found in cruciferous vegetables." @default.
- NCIT_C1135 NCIT_P325 "An indole with a carbinol group (-C2OH) attached at the 3 position of the pyrrole ring. The chemical structure is C1=CC=C2C(=C1)C(=CN2)CO." @default.
- NCIT_C1135 NCIT_P329 "38058" @default.
- NCIT_C1135 NCIT_P330 "38058" @default.
- NCIT_C1135 NCIT_P350 "C9H9NO" @default.
- NCIT_C1135 NCIT_P366 "Indole-3-Carbinol" @default.
- NCIT_C1135 NCIT_P368 "CHEBI:24814" @default.
- NCIT_C1135 NCIT_P375 "Indole-3-Carbinol" @default.
- NCIT_C1135 NCIT_P399 "38058" @default.
- NCIT_C1135 normalizedInformationContent "100" @default.
- NCIT_C1135 referenceCount "1" @default.
- NCIT_C1135 hasExactSynonym "1H-indole-3-methanol" @default.
- NCIT_C1135 hasExactSynonym "3-Hydroxymethylindole" @default.
- NCIT_C1135 hasExactSynonym "I3C" @default.
- NCIT_C1135 hasExactSynonym "INDOLE-3-CARBINOL" @default.
- NCIT_C1135 hasExactSynonym "Indole-3-Carbinol" @default.
- NCIT_C1135 hasExactSynonym "Indole-3-carbinol" @default.
- NCIT_C1135 hasExactSynonym "Indole-3-methanol" @default.
- NCIT_C1135 hasExactSynonym "indole-3-carbinol" @default.
- NCIT_C1135 inSubset NCIT_C116977 @default.
- NCIT_C1135 inSubset NCIT_C116978 @default.
- NCIT_C1135 inSubset NCIT_C128784 @default.
- NCIT_C1135 inSubset NCIT_C157711 @default.
- NCIT_C1135 inSubset NCIT_C157712 @default.
- NCIT_C1135 inSubset NCIT_C176424 @default.
- NCIT_C1135 inSubset NCIT_C177537 @default.
- NCIT_C1135 inSubset NCIT_C63923 @default.
- NCIT_C1135 type Class @default.
- NCIT_C1135 isDefinedBy ncit.owl @default.
- NCIT_C1135 label "Indole-3-Carbinol" @default.
- NCIT_C1135 subClassOf NCIT_C1135 @default.
- NCIT_C1135 subClassOf NCIT_C1908 @default.
- NCIT_C1135 subClassOf NCIT_C1930 @default.
- NCIT_C1135 subClassOf NCIT_C1949 @default.
- NCIT_C1135 subClassOf NCIT_C54060 @default.