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- NCIT_C113795 IAO_0000115 "An immediate-release (IR) formulation of onapristone, an orally bioavailable progesterone receptor (PR) antagonist, with antineoplastic activity. Onapristone binds to the PR and inhibits both PR activation and the associated expression of PR-responsive genes. This may inhibit PR-mediated proliferative effects in cancer cells overexpressing PR. PR is expressed on certain cancer cell types and plays a key role in proliferation and survival." @default.
- NCIT_C113795 NCIT_A32 NCIT_C1909 @default.
- NCIT_C113795 NCIT_NHC0 "C113795" @default.
- NCIT_C113795 NCIT_P106 "Organic Chemical" @default.
- NCIT_C113795 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C113795 NCIT_P108 "Immediate-release Onapristone" @default.
- NCIT_C113795 NCIT_P208 "CL471777" @default.
- NCIT_C113795 NCIT_P322 "GDC" @default.
- NCIT_C113795 NCIT_P329 "757590" @default.
- NCIT_C113795 NCIT_P330 "757590" @default.
- NCIT_C113795 NCIT_P375 "Immediate-release Onapristone" @default.
- NCIT_C113795 NCIT_P399 "757590" @default.
- NCIT_C113795 normalizedInformationContent "100" @default.
- NCIT_C113795 referenceCount "1" @default.
- NCIT_C113795 hasExactSynonym "IR Onapristone" @default.
- NCIT_C113795 hasExactSynonym "Immediate-release Onapristone" @default.
- NCIT_C113795 inSubset NCIT_C128784 @default.
- NCIT_C113795 inSubset NCIT_C157711 @default.
- NCIT_C113795 inSubset NCIT_C157712 @default.
- NCIT_C113795 inSubset NCIT_C176424 @default.
- NCIT_C113795 inSubset NCIT_C177537 @default.
- NCIT_C113795 type Class @default.
- NCIT_C113795 isDefinedBy ncit.owl @default.
- NCIT_C113795 label "Immediate-release Onapristone" @default.
- NCIT_C113795 subClassOf NCIT_C113795 @default.
- NCIT_C113795 subClassOf NCIT_C147908 @default.
- NCIT_C113795 subClassOf NCIT_C1891 @default.
- NCIT_C113795 subClassOf NCIT_C1908 @default.
- NCIT_C113795 subClassOf NCIT_C1909 @default.
- NCIT_C113795 subClassOf NCIT_C547 @default.