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- NCIT_C113799 IAO_0000115 "An extract of Uncaria tomentosa (U. tomentosa), also called Cat's claw, a native Amazonian plant belonging to the Rubiaceae species, with potential anti-inflammatory, immunomodulating, antioxidant and antineoplastic activities. Although the exact mechanism(s) by which U. tomentosa extract exerts its effect(s) has yet to be fully elucidated, this extract may inhibit the proliferation of certain types of cancer cells. This extract may modulate inflammatory and immune responses through the stimulation of T- and B-lymphocytes and certain cytokines, including interleukin (IL)-1, IL-6 and tumor necrosis factor-alpha (TNF-a). Components in U. tomentosa may both induce repair of chemically-induced DNA damage and scavenge free radicals, which may protect against reactive oxygen species (ROS)-mediated cellular damage. In addition, this extract stimulates myelopoiesis, which may prevent chemotherapy-induced neutropenia." @default.
- NCIT_C113799 NCIT_A32 NCIT_C1909 @default.
- NCIT_C113799 NCIT_NHC0 "C113799" @default.
- NCIT_C113799 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C113799 NCIT_P108 "Uncaria tomentosa Extract" @default.
- NCIT_C113799 NCIT_P207 "C0939876" @default.
- NCIT_C113799 NCIT_P319 "9060PRM18Q" @default.
- NCIT_C113799 NCIT_P322 "FDA" @default.
- NCIT_C113799 NCIT_P322 "GDC" @default.
- NCIT_C113799 NCIT_P329 "757651" @default.
- NCIT_C113799 NCIT_P330 "757651" @default.
- NCIT_C113799 NCIT_P375 "Uncaria tomentosa Extract" @default.
- NCIT_C113799 NCIT_P399 "757651" @default.
- NCIT_C113799 normalizedInformationContent "100" @default.
- NCIT_C113799 referenceCount "1" @default.
- NCIT_C113799 hasExactSynonym "CAT'S CLAW" @default.
- NCIT_C113799 hasExactSynonym "Cat's Claw Herbal Extract" @default.
- NCIT_C113799 hasExactSynonym "Uncaria tomentosa Extract" @default.
- NCIT_C113799 inSubset NCIT_C128784 @default.
- NCIT_C113799 inSubset NCIT_C157711 @default.
- NCIT_C113799 inSubset NCIT_C157712 @default.
- NCIT_C113799 inSubset NCIT_C176424 @default.
- NCIT_C113799 inSubset NCIT_C177537 @default.
- NCIT_C113799 inSubset NCIT_C63923 @default.
- NCIT_C113799 type Class @default.
- NCIT_C113799 isDefinedBy ncit.owl @default.
- NCIT_C113799 label "Uncaria tomentosa Extract" @default.
- NCIT_C113799 subClassOf NCIT_C113799 @default.
- NCIT_C113799 subClassOf NCIT_C1908 @default.
- NCIT_C113799 subClassOf NCIT_C1909 @default.
- NCIT_C113799 subClassOf NCIT_C26170 @default.
- NCIT_C113799 subClassOf NCIT_C275 @default.
- NCIT_C113799 subClassOf NCIT_C78284 @default.