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- NCIT_C114284 IAO_0000115 "A cell lysate derived from a lung cancer cell line, H1299, with potential immunostimulatory and antineoplastic activities. Upon intramuscular administration, the H1299 tumor cell lysate exposes the immune system to an undefined amount of tumor associated antigens (TAA), particularly cancer testis antigens (CTAs), which may result in the induction of both anti-tumoral cytotoxic T-lymphocytes (CTL) and antibody-dependent responses against TAA-expressing cells, leading to tumor cell lysis. CTAs, such as MAGE, are selectively expressed in a variety of cancers but are not expressed in normal, healthy cells outside the testis." @default.
- NCIT_C114284 NCIT_A32 NCIT_C1909 @default.
- NCIT_C114284 NCIT_NHC0 "C114284" @default.
- NCIT_C114284 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C114284 NCIT_P108 "H1299 Tumor Cell Lysate Vaccine" @default.
- NCIT_C114284 NCIT_P208 "CL471792" @default.
- NCIT_C114284 NCIT_P322 "GDC" @default.
- NCIT_C114284 NCIT_P329 "757927" @default.
- NCIT_C114284 NCIT_P330 "757927" @default.
- NCIT_C114284 NCIT_P375 "H1299 Tumor Cell Lysate Vaccine" @default.
- NCIT_C114284 NCIT_P399 "757927" @default.
- NCIT_C114284 normalizedInformationContent "100" @default.
- NCIT_C114284 referenceCount "1" @default.
- NCIT_C114284 hasExactSynonym "H1299 Lysate Vaccine" @default.
- NCIT_C114284 hasExactSynonym "H1299 Tumor Cell Lysate Vaccine" @default.
- NCIT_C114284 inSubset NCIT_C128784 @default.
- NCIT_C114284 inSubset NCIT_C157711 @default.
- NCIT_C114284 inSubset NCIT_C157712 @default.
- NCIT_C114284 inSubset NCIT_C176424 @default.
- NCIT_C114284 inSubset NCIT_C177537 @default.
- NCIT_C114284 type Class @default.
- NCIT_C114284 isDefinedBy ncit.owl @default.
- NCIT_C114284 label "H1299 Tumor Cell Lysate Vaccine" @default.
- NCIT_C114284 subClassOf NCIT_C114284 @default.
- NCIT_C114284 subClassOf NCIT_C129820 @default.
- NCIT_C114284 subClassOf NCIT_C1663 @default.
- NCIT_C114284 subClassOf NCIT_C1908 @default.
- NCIT_C114284 subClassOf NCIT_C1909 @default.
- NCIT_C114284 subClassOf NCIT_C274 @default.
- NCIT_C114284 subClassOf NCIT_C307 @default.
- NCIT_C114284 subClassOf NCIT_C308 @default.
- NCIT_C114284 subClassOf NCIT_C923 @default.