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- NCIT_C114286 IAO_0000115 "A monoclonal antibody directed against the cell surface protein claudin 6 (CLDN6), with potential immunostimulating and antineoplastic activities. Upon administration, the anti-CLDN6 monoclonal antibody ASP1650 binds to CLDN-6 and may stimulate the immune system to exert both an antibody-dependent cellular cytotoxicity (ADCC) and a complement-dependent cytotoxicity (CDC) mediated immune response against CLDN-6-expressing tumor cells. This may inhibit tumor cell growth. CLDN-6, a tight-junction protein and embryonic antigen, is expressed on a variety of tumor cells but is not expressed on normal, healthy adult cells." @default.
- NCIT_C114286 NCIT_A32 NCIT_C1909 @default.
- NCIT_C114286 NCIT_A7 NCIT_C117145 @default.
- NCIT_C114286 NCIT_NHC0 "C114286" @default.
- NCIT_C114286 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C114286 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C114286 NCIT_P107 "Anti-CLDN6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 NCIT_P108 "Anti-CLDN6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 NCIT_P208 "CL471794" @default.
- NCIT_C114286 NCIT_P322 "CTRP" @default.
- NCIT_C114286 NCIT_P322 "GDC" @default.
- NCIT_C114286 NCIT_P329 "757981" @default.
- NCIT_C114286 NCIT_P330 "757981" @default.
- NCIT_C114286 NCIT_P375 "Anti-CLDN6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 NCIT_P399 "757981" @default.
- NCIT_C114286 NCIT_R124 NCIT_C17710 @default.
- NCIT_C114286 NCIT_R124 NCIT_C17828 @default.
- NCIT_C114286 NCIT_R124 NCIT_C18219 @default.
- NCIT_C114286 NCIT_R124 NCIT_C19986 @default.
- NCIT_C114286 NCIT_R124 NCIT_C40474 @default.
- NCIT_C114286 normalizedInformationContent "100" @default.
- NCIT_C114286 referenceCount "1" @default.
- NCIT_C114286 hasExactSynonym "ASP 1650" @default.
- NCIT_C114286 hasExactSynonym "ASP-1650" @default.
- NCIT_C114286 hasExactSynonym "ASP1650" @default.
- NCIT_C114286 hasExactSynonym "Anti-CLDN6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 hasExactSynonym "Anti-Claudin 6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 hasExactSynonym "IMAB027" @default.
- NCIT_C114286 inSubset NCIT_C116977 @default.
- NCIT_C114286 inSubset NCIT_C116978 @default.
- NCIT_C114286 inSubset NCIT_C128784 @default.
- NCIT_C114286 inSubset NCIT_C157711 @default.
- NCIT_C114286 inSubset NCIT_C157712 @default.
- NCIT_C114286 inSubset NCIT_C176424 @default.
- NCIT_C114286 inSubset NCIT_C177537 @default.
- NCIT_C114286 type Class @default.
- NCIT_C114286 isDefinedBy ncit.owl @default.
- NCIT_C114286 label "Anti-CLDN6 Monoclonal Antibody ASP1650" @default.
- NCIT_C114286 subClassOf NCIT_C114286 @default.
- NCIT_C114286 subClassOf NCIT_C129821 @default.
- NCIT_C114286 subClassOf NCIT_C129822 @default.
- NCIT_C114286 subClassOf NCIT_C1908 @default.
- NCIT_C114286 subClassOf NCIT_C1909 @default.
- NCIT_C114286 subClassOf NCIT_C20401 @default.
- NCIT_C114286 subClassOf NCIT_C274 @default.
- NCIT_C114286 subClassOf NCIT_C307 @default.
- NCIT_C114286 subClassOf NCIT_C308 @default.