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- NCIT_C114292 IAO_0000115 "A solution composed of iodine and potassium iodide, which can be used as a reagent and antiseptic, with potential use in cancer diagnosis. The iodine in Lugol's solution selectively binds to alpha-1,4 glucans found in polysaccharides, such as glycogen. Lugol's solution reacts with glycogen in normal, healthy non-keratinized, squamous epithelium and the iodine-glucan complex stains the glycogen-containing cells dark brown. Cancer cells are devoid of glycogen, so these cells will stay unstained. The presence of cancer cells can be detected by the degree of staining and the neoplastic cells can be surgically removed. High-grade intraepitheial neoplasia has almost no glycogen-containing epithelium." @default.
- NCIT_C114292 NCIT_NHC0 "C114292" @default.
- NCIT_C114292 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C114292 NCIT_P107 "Lugol's Solution" @default.
- NCIT_C114292 NCIT_P108 "Lugol's Solution" @default.
- NCIT_C114292 NCIT_P207 "C0065234" @default.
- NCIT_C114292 NCIT_P322 "CTRP" @default.
- NCIT_C114292 NCIT_P329 "758107" @default.
- NCIT_C114292 NCIT_P330 "758107" @default.
- NCIT_C114292 NCIT_P399 "758107" @default.
- NCIT_C114292 normalizedInformationContent "100" @default.
- NCIT_C114292 referenceCount "1" @default.
- NCIT_C114292 hasExactSynonym "Lugol's Iodine" @default.
- NCIT_C114292 hasExactSynonym "Lugol's Solution" @default.
- NCIT_C114292 inSubset NCIT_C116977 @default.
- NCIT_C114292 inSubset NCIT_C116978 @default.
- NCIT_C114292 inSubset NCIT_C176424 @default.
- NCIT_C114292 type Class @default.
- NCIT_C114292 isDefinedBy ncit.owl @default.
- NCIT_C114292 label "Lugol's Solution" @default.
- NCIT_C114292 subClassOf NCIT_C114292 @default.
- NCIT_C114292 subClassOf NCIT_C1908 @default.
- NCIT_C114292 subClassOf NCIT_C1937 @default.
- NCIT_C114292 subClassOf NCIT_C45678 @default.
- NCIT_C114292 subClassOf NCIT_C802 @default.