Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C115107> ?p ?o ?g. }
Showing items 1 to 25 of
25
with 100 items per page.
- NCIT_C115107 IAO_0000115 "A population of closely human leukocyte antigen (HLA)-matched, donor-derived cytotoxic T lymphocytes (CTLs) that are specifically reactive towards five viruses, Epstein-Barr virus (EBV), cytomegalovirus (CMV), adenovirus (AdV), human herpesvirus 6 (HHV6), and human polyomavirus type I (BKV), with potential antiviral activity. Infusion of the multivirus-specific CTLs into allogeneic hematopoietic stem cell transplant (HSCT) recipients provides virus-specific cellular immunity and causes specific anti-viral effects against active viral infections. The administered CTLs also prevent EBV, CMV, AdV, HHV6, and BKV reactivation and infection as well as inhibiting viral-associated diseases in immunocompromised patients. The allogeneic multivirus-specific CTLs may also provide cellular immunity towards the human polyomavirus type II (JC virus; JCV), which is highly homologous to BKV." @default.
- NCIT_C115107 NCIT_NHC0 "C115107" @default.
- NCIT_C115107 NCIT_P106 "Cell" @default.
- NCIT_C115107 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C115107 NCIT_P108 "Allogeneic Multivirus-specific Cytotoxic T Lymphocytes" @default.
- NCIT_C115107 NCIT_P208 "CL472638" @default.
- NCIT_C115107 NCIT_P329 "759975" @default.
- NCIT_C115107 NCIT_P330 "759975" @default.
- NCIT_C115107 NCIT_P399 "759975" @default.
- NCIT_C115107 normalizedInformationContent "100" @default.
- NCIT_C115107 referenceCount "1" @default.
- NCIT_C115107 hasExactSynonym "Allogeneic EBV/CMV/AdV/HHV6/BKV-specific CTLs" @default.
- NCIT_C115107 hasExactSynonym "Allogeneic Multivirus-specific CTLs" @default.
- NCIT_C115107 hasExactSynonym "Allogeneic Multivirus-specific Cytotoxic T Lymphocytes" @default.
- NCIT_C115107 inSubset NCIT_C176424 @default.
- NCIT_C115107 type Class @default.
- NCIT_C115107 isDefinedBy ncit.owl @default.
- NCIT_C115107 label "Allogeneic Multivirus-specific Cytotoxic T Lymphocytes" @default.
- NCIT_C115107 subClassOf NCIT_C115107 @default.
- NCIT_C115107 subClassOf NCIT_C142078 @default.
- NCIT_C115107 subClassOf NCIT_C1908 @default.
- NCIT_C115107 subClassOf NCIT_C1909 @default.
- NCIT_C115107 subClassOf NCIT_C28676 @default.
- NCIT_C115107 subClassOf NCIT_C307 @default.
- NCIT_C115107 subClassOf NCIT_C308 @default.