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- NCIT_C115111 IAO_0000115 "A carbohydrate-based galectin inhibitor, with potential antineoplastic activity. Belapectin binds to the carbohydrate-binding domain of galectins, especially galectin-3, and may result in an induction of apoptosis mediated through activation of both mitochondria and caspases. This may reduce tumor growth in galectin-overexpressing tumor cells. Galectins, often overexpressed on tumor cells, play a key role in cancer cell proliferation, apoptosis, tumor angiogenesis and evasion of immune responses." @default.
- NCIT_C115111 NCIT_A32 NCIT_C1909 @default.
- NCIT_C115111 NCIT_A7 NCIT_C104859 @default.
- NCIT_C115111 NCIT_NHC0 "C115111" @default.
- NCIT_C115111 NCIT_P106 "Nucleic Acid, Nucleoside, or Nucleotide" @default.
- NCIT_C115111 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C115111 NCIT_P107 "Belapectin" @default.
- NCIT_C115111 NCIT_P108 "Belapectin" @default.
- NCIT_C115111 NCIT_P208 "CL472642" @default.
- NCIT_C115111 NCIT_P210 "1980787-47-0" @default.
- NCIT_C115111 NCIT_P319 "K7ODU55HT6" @default.
- NCIT_C115111 NCIT_P322 "CTRP" @default.
- NCIT_C115111 NCIT_P322 "FDA" @default.
- NCIT_C115111 NCIT_P322 "GDC" @default.
- NCIT_C115111 NCIT_P329 "760131" @default.
- NCIT_C115111 NCIT_P330 "760131" @default.
- NCIT_C115111 NCIT_P375 "Belapectin" @default.
- NCIT_C115111 NCIT_P375 "Galectin Inhibitor GR-MD-02" @default.
- NCIT_C115111 NCIT_P399 "760131" @default.
- NCIT_C115111 normalizedInformationContent "100" @default.
- NCIT_C115111 referenceCount "1" @default.
- NCIT_C115111 hasExactSynonym "BELAPECTIN" @default.
- NCIT_C115111 hasExactSynonym "Belapectin" @default.
- NCIT_C115111 hasExactSynonym "GR-MD-02" @default.
- NCIT_C115111 hasExactSynonym "Galactoarabino-rhamnogalacturonate" @default.
- NCIT_C115111 inSubset NCIT_C116977 @default.
- NCIT_C115111 inSubset NCIT_C116978 @default.
- NCIT_C115111 inSubset NCIT_C128784 @default.
- NCIT_C115111 inSubset NCIT_C157711 @default.
- NCIT_C115111 inSubset NCIT_C157712 @default.
- NCIT_C115111 inSubset NCIT_C176424 @default.
- NCIT_C115111 inSubset NCIT_C177537 @default.
- NCIT_C115111 inSubset NCIT_C63923 @default.
- NCIT_C115111 type Class @default.
- NCIT_C115111 isDefinedBy ncit.owl @default.
- NCIT_C115111 label "Belapectin" @default.
- NCIT_C115111 subClassOf NCIT_C115111 @default.
- NCIT_C115111 subClassOf NCIT_C129839 @default.
- NCIT_C115111 subClassOf NCIT_C1908 @default.
- NCIT_C115111 subClassOf NCIT_C1909 @default.
- NCIT_C115111 subClassOf NCIT_C274 @default.