Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C116068> ?p ?o ?g. }
Showing items 1 to 48 of
48
with 100 items per page.
- NCIT_C116068 IAO_0000115 "An orally bioavailable inhibitor of the serine/threonine protein kinase aurora A, with potential antimitotic and antineoplastic activities. Upon intravenous administration, aurora A kinase inhibitor VIC-1911 binds to and inhibits aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, inhibition of cell division and the induction of apoptosis in cells overexpressing aurora A kinase. Aurora A kinase localizes to the spindle poles and to spindle microtubules during mitosis; it plays an essential role in the regulation of spindle assembly. Aurora kinase A is overexpressed in a wide variety of cancers." @default.
- NCIT_C116068 NCIT_A32 NCIT_C1909 @default.
- NCIT_C116068 NCIT_NHC0 "C116068" @default.
- NCIT_C116068 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C116068 NCIT_P108 "Aurora A Kinase Inhibitor VIC-1911" @default.
- NCIT_C116068 NCIT_P208 "CL473487" @default.
- NCIT_C116068 NCIT_P322 "GDC" @default.
- NCIT_C116068 NCIT_P329 "760907" @default.
- NCIT_C116068 NCIT_P330 "760907" @default.
- NCIT_C116068 NCIT_P375 "Aurora A Kinase Inhibitor TAS-119" @default.
- NCIT_C116068 NCIT_P399 "760907" @default.
- NCIT_C116068 NCIT_R146 NCIT_C16554 @default.
- NCIT_C116068 NCIT_R146 NCIT_C16984 @default.
- NCIT_C116068 NCIT_R146 NCIT_C17018 @default.
- NCIT_C116068 NCIT_R146 NCIT_C17021 @default.
- NCIT_C116068 NCIT_R146 NCIT_C17210 @default.
- NCIT_C116068 NCIT_R146 NCIT_C17325 @default.
- NCIT_C116068 NCIT_R146 NCIT_C20027 @default.
- NCIT_C116068 NCIT_R146 NCIT_C26548 @default.
- NCIT_C116068 NCIT_R146 NCIT_C30006 @default.
- NCIT_C116068 normalizedInformationContent "100" @default.
- NCIT_C116068 referenceCount "1" @default.
- NCIT_C116068 hasExactSynonym "Aurora A Kinase Inhibitor TAS-119" @default.
- NCIT_C116068 hasExactSynonym "Aurora A Kinase Inhibitor VIC-1911" @default.
- NCIT_C116068 hasExactSynonym "TAS-119" @default.
- NCIT_C116068 hasExactSynonym "TAS-2104" @default.
- NCIT_C116068 hasExactSynonym "VIC 1911" @default.
- NCIT_C116068 hasExactSynonym "VIC-1911" @default.
- NCIT_C116068 hasExactSynonym "VIC1911" @default.
- NCIT_C116068 inSubset NCIT_C128784 @default.
- NCIT_C116068 inSubset NCIT_C157711 @default.
- NCIT_C116068 inSubset NCIT_C157712 @default.
- NCIT_C116068 inSubset NCIT_C176424 @default.
- NCIT_C116068 inSubset NCIT_C177537 @default.
- NCIT_C116068 type Class @default.
- NCIT_C116068 isDefinedBy ncit.owl @default.
- NCIT_C116068 label "Aurora A Kinase Inhibitor VIC-1911" @default.
- NCIT_C116068 subClassOf NCIT_C116068 @default.
- NCIT_C116068 subClassOf NCIT_C129824 @default.
- NCIT_C116068 subClassOf NCIT_C129825 @default.
- NCIT_C116068 subClassOf NCIT_C1404 @default.
- NCIT_C116068 subClassOf NCIT_C1908 @default.
- NCIT_C116068 subClassOf NCIT_C1909 @default.
- NCIT_C116068 subClassOf NCIT_C2189 @default.
- NCIT_C116068 subClassOf NCIT_C274 @default.
- NCIT_C116068 subClassOf NCIT_C471 @default.
- NCIT_C116068 subClassOf NCIT_C61074 @default.
- NCIT_C116068 subClassOf NCIT_C62556 @default.