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- NCIT_C116618 IAO_0000115 "A non-metabolizable glucose analog in which the hydroxyl group at position 2 of glucose is replaced by hydrogen, with potential glycolysis inhibiting and antineoplastic activities. Although the exact mechanism of action has yet to be fully elucidated, upon administration of 2-deoxy-D-glucose (2-DG), this agent competes with glucose for uptake by proliferating cells, such as tumor cells. 2-DG inhibits the first step of glycolysis and therefore prevents cellular energy production, which may result in decreased tumor cell proliferation." @default.
- NCIT_C116618 NCIT_A32 NCIT_C1909 @default.
- NCIT_C116618 NCIT_NHC0 "C116618" @default.
- NCIT_C116618 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C116618 NCIT_P107 "2-Deoxy-D-glucose" @default.
- NCIT_C116618 NCIT_P108 "2-Deoxy-D-glucose" @default.
- NCIT_C116618 NCIT_P207 "C0011501" @default.
- NCIT_C116618 NCIT_P210 "154-17-6" @default.
- NCIT_C116618 NCIT_P319 "9G2MP84A8W" @default.
- NCIT_C116618 NCIT_P322 "CTRP" @default.
- NCIT_C116618 NCIT_P322 "FDA" @default.
- NCIT_C116618 NCIT_P322 "GDC" @default.
- NCIT_C116618 NCIT_P329 "409701" @default.
- NCIT_C116618 NCIT_P330 "409701" @default.
- NCIT_C116618 NCIT_P375 "2-Deoxy-D-glucose" @default.
- NCIT_C116618 NCIT_P399 "409701" @default.
- NCIT_C116618 normalizedInformationContent "100" @default.
- NCIT_C116618 referenceCount "1" @default.
- NCIT_C116618 hasExactSynonym "2-DEOXYGLUCOSE" @default.
- NCIT_C116618 hasExactSynonym "2-DG" @default.
- NCIT_C116618 hasExactSynonym "2-Deoxy-D-glucose" @default.
- NCIT_C116618 hasExactSynonym "Deoxyglucose" @default.
- NCIT_C116618 inSubset NCIT_C116977 @default.
- NCIT_C116618 inSubset NCIT_C116978 @default.
- NCIT_C116618 inSubset NCIT_C128784 @default.
- NCIT_C116618 inSubset NCIT_C157711 @default.
- NCIT_C116618 inSubset NCIT_C157712 @default.
- NCIT_C116618 inSubset NCIT_C176424 @default.
- NCIT_C116618 inSubset NCIT_C177537 @default.
- NCIT_C116618 inSubset NCIT_C63923 @default.
- NCIT_C116618 type Class @default.
- NCIT_C116618 isDefinedBy ncit.owl @default.
- NCIT_C116618 label "2-Deoxy-D-glucose" @default.
- NCIT_C116618 subClassOf NCIT_C116618 @default.
- NCIT_C116618 subClassOf NCIT_C1908 @default.
- NCIT_C116618 subClassOf NCIT_C1913 @default.
- NCIT_C116618 subClassOf NCIT_C344 @default.
- NCIT_C116618 subClassOf NCIT_C718 @default.