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- NCIT_C116733 IAO_0000115 "A plasmid DNA vaccine encoding an autologous lymphoma-derived idiotype-targeting immunoglobulin (Ig)-derived single chain variable fragment (scFv) fused to the chemokine macrophage inflammatory protein 3 alpha (MIP3a), with potential immunostimulating and antineoplastic activities. Upon intramuscular vaccination, the autologous lymphoma immunoglobulin-derived scFv-chemokine DNA vaccine is taken up by antigen-presenting cells (APCs) and stimulates the immune system to exert a cytotoxic T-lymphocyte (CTL) response against the idiotype expressed on the surface of B lymphoma cells. MIP3a, also called chemokine (C-C motif) ligand 20 (CCL20), is a chemotactic cytokine able to enhance the immune response through binding to chemokine receptors expressed on APCs." @default.
- NCIT_C116733 NCIT_NHC0 "C116733" @default.
- NCIT_C116733 NCIT_P106 "Gene or Genome" @default.
- NCIT_C116733 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C116733 NCIT_P107 "Autologous Lymphoma Immunoglobulin-derived scFV-chemokine DNA Vaccine" @default.
- NCIT_C116733 NCIT_P108 "Autologous Lymphoma Immunoglobulin-derived scFv-chemokine DNA Vaccine" @default.
- NCIT_C116733 NCIT_P208 "CL433717" @default.
- NCIT_C116733 NCIT_P322 "CTRP" @default.
- NCIT_C116733 NCIT_P329 "686535" @default.
- NCIT_C116733 NCIT_P330 "686535" @default.
- NCIT_C116733 NCIT_P399 "686535" @default.
- NCIT_C116733 NCIT_R125 NCIT_C17828 @default.
- NCIT_C116733 NCIT_R125 NCIT_C17937 @default.
- NCIT_C116733 NCIT_R125 NCIT_C18095 @default.
- NCIT_C116733 NCIT_R125 NCIT_C18839 @default.
- NCIT_C116733 NCIT_R125 NCIT_C21124 @default.
- NCIT_C116733 NCIT_R125 NCIT_C40912 @default.
- NCIT_C116733 normalizedInformationContent "100" @default.
- NCIT_C116733 referenceCount "1" @default.
- NCIT_C116733 hasExactSynonym "Autologous Lymphoma Immunoglobulin-derived scFV-chemokine DNA Vaccine" @default.
- NCIT_C116733 hasExactSynonym "Autologous Lymphoma Immunoglobulin-derived scFv-chemokine DNA Vaccine" @default.
- NCIT_C116733 inSubset NCIT_C116977 @default.
- NCIT_C116733 inSubset NCIT_C116978 @default.
- NCIT_C116733 inSubset NCIT_C128784 @default.
- NCIT_C116733 inSubset NCIT_C176424 @default.
- NCIT_C116733 type Class @default.
- NCIT_C116733 isDefinedBy ncit.owl @default.
- NCIT_C116733 label "Autologous Lymphoma Immunoglobulin-derived scFv-chemokine DNA Vaccine" @default.
- NCIT_C116733 subClassOf B5d1393fb8034207033748bcd4c63cef8 @default.
- NCIT_C116733 subClassOf B87d7cf459a45a1fd04526116a2ebac45 @default.
- NCIT_C116733 subClassOf NCIT_C116733 @default.
- NCIT_C116733 subClassOf NCIT_C129820 @default.
- NCIT_C116733 subClassOf NCIT_C1663 @default.
- NCIT_C116733 subClassOf NCIT_C1908 @default.
- NCIT_C116733 subClassOf NCIT_C1909 @default.
- NCIT_C116733 subClassOf NCIT_C274 @default.
- NCIT_C116733 subClassOf NCIT_C307 @default.
- NCIT_C116733 subClassOf NCIT_C308 @default.
- NCIT_C116733 subClassOf NCIT_C39619 @default.
- NCIT_C116733 subClassOf NCIT_C923 @default.