Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C116857> ?p ?o ?g. }
Showing items 1 to 45 of
45
with 100 items per page.
- NCIT_C116857 IAO_0000115 "An orally bioavailable imidazopyridazine and inhibitor of Janus kinase 2 mutant V617F (JAK2V617F), with potential antineoplastic activity. Upon oral administration, gandotinib selectively and competitively inhibits the activation of JAK2V617F, which may result in the inhibition of the JAK-STAT signaling pathway and the induction of apoptosis in JAK2V617F-expressing tumor cells. JAK2V617F has a substitution of phenylalanine for valine at amino acid position 617 and plays a key role in tumor cell proliferation and survival." @default.
- NCIT_C116857 NCIT_A32 NCIT_C1909 @default.
- NCIT_C116857 NCIT_A7 NCIT_C105908 @default.
- NCIT_C116857 NCIT_NHC0 "C116857" @default.
- NCIT_C116857 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C116857 NCIT_P107 "Gandotinib" @default.
- NCIT_C116857 NCIT_P108 "Gandotinib" @default.
- NCIT_C116857 NCIT_P207 "C3659426" @default.
- NCIT_C116857 NCIT_P210 "1229236-86-5" @default.
- NCIT_C116857 NCIT_P319 "ANC71R916O" @default.
- NCIT_C116857 NCIT_P322 "CTRP" @default.
- NCIT_C116857 NCIT_P322 "FDA" @default.
- NCIT_C116857 NCIT_P322 "GDC" @default.
- NCIT_C116857 NCIT_P329 "682801" @default.
- NCIT_C116857 NCIT_P330 "682801" @default.
- NCIT_C116857 NCIT_P375 "Gandotinib" @default.
- NCIT_C116857 NCIT_P399 "682801" @default.
- NCIT_C116857 normalizedInformationContent "100" @default.
- NCIT_C116857 referenceCount "1" @default.
- NCIT_C116857 hasExactSynonym "3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(Morpholinomethyl)imidazo(1,2-b)pyridazin-6-amine" @default.
- NCIT_C116857 hasExactSynonym "GANDOTINIB" @default.
- NCIT_C116857 hasExactSynonym "Gandotinib" @default.
- NCIT_C116857 hasExactSynonym "LY 2784544" @default.
- NCIT_C116857 hasExactSynonym "LY2784544" @default.
- NCIT_C116857 inSubset NCIT_C116977 @default.
- NCIT_C116857 inSubset NCIT_C116978 @default.
- NCIT_C116857 inSubset NCIT_C128784 @default.
- NCIT_C116857 inSubset NCIT_C157711 @default.
- NCIT_C116857 inSubset NCIT_C157712 @default.
- NCIT_C116857 inSubset NCIT_C176424 @default.
- NCIT_C116857 inSubset NCIT_C177537 @default.
- NCIT_C116857 inSubset NCIT_C63923 @default.
- NCIT_C116857 type Class @default.
- NCIT_C116857 isDefinedBy ncit.owl @default.
- NCIT_C116857 label "Gandotinib" @default.
- NCIT_C116857 subClassOf NCIT_C116857 @default.
- NCIT_C116857 subClassOf NCIT_C129824 @default.
- NCIT_C116857 subClassOf NCIT_C129825 @default.
- NCIT_C116857 subClassOf NCIT_C1404 @default.
- NCIT_C116857 subClassOf NCIT_C1908 @default.
- NCIT_C116857 subClassOf NCIT_C1909 @default.
- NCIT_C116857 subClassOf NCIT_C1967 @default.
- NCIT_C116857 subClassOf NCIT_C2189 @default.
- NCIT_C116857 subClassOf NCIT_C274 @default.
- NCIT_C116857 subClassOf NCIT_C471 @default.