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- NCIT_C116887 IAO_0000115 "A radioconjugate composed of an urea-based human prostate-specific membrane antigen (PSMA)-targeting ligand, conjugated to the gamma-emitting radioisotope technetium Tc 99m, with potential use as a tracer for PSMA-expressing tumors using single photon emission computed tomography/computed tomography (SPECT/CT). Upon intravenous administration of the technetium Tc 99m trofolastat, the trofolastat moiety targets and binds to PSMA-expressing tumor cells. Upon internalization, PSMA-expressing tumor cells can be detected during SPECT/CT imaging. PSMA, a tumor-associated antigen and type II transmembrane protein, is expressed on the membrane of prostatic epithelial cells and overexpressed on prostate tumor cells." @default.
- NCIT_C116887 NCIT_A7 NCIT_C17796 @default.
- NCIT_C116887 NCIT_NHC0 "C116887" @default.
- NCIT_C116887 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C116887 NCIT_P107 "Technetium Tc 99m Trofolastat" @default.
- NCIT_C116887 NCIT_P108 "Technetium Tc 99m Trofolastat" @default.
- NCIT_C116887 NCIT_P207 "C4045172" @default.
- NCIT_C116887 NCIT_P210 "1660954-70-0" @default.
- NCIT_C116887 NCIT_P322 "CTRP" @default.
- NCIT_C116887 NCIT_P329 "691686" @default.
- NCIT_C116887 NCIT_P330 "691686" @default.
- NCIT_C116887 NCIT_P399 "691686" @default.
- NCIT_C116887 normalizedInformationContent "100" @default.
- NCIT_C116887 referenceCount "1" @default.
- NCIT_C116887 hasExactSynonym "99mTc-MIP 1404" @default.
- NCIT_C116887 hasExactSynonym "99mTc-MIP-1404" @default.
- NCIT_C116887 hasExactSynonym "Technetium Tc 99m Trofolastat" @default.
- NCIT_C116887 inSubset NCIT_C116977 @default.
- NCIT_C116887 inSubset NCIT_C116978 @default.
- NCIT_C116887 inSubset NCIT_C176424 @default.
- NCIT_C116887 type Class @default.
- NCIT_C116887 isDefinedBy ncit.owl @default.
- NCIT_C116887 label "Technetium Tc 99m Trofolastat" @default.
- NCIT_C116887 subClassOf NCIT_C116887 @default.
- NCIT_C116887 subClassOf NCIT_C1446 @default.
- NCIT_C116887 subClassOf NCIT_C1908 @default.
- NCIT_C116887 subClassOf NCIT_C1909 @default.
- NCIT_C116887 subClassOf NCIT_C2124 @default.