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- NCIT_C117725 IAO_0000115 "A vaccine consisting of lethally irradiated human fetal lung fibroblasts (Medical Research Council 5 or MRC-5) transfected with autologous tumor DNA derived from a head and neck squamous cell carcinoma (HNSCC), with potential immunostimulatory and antineoplastic activities. Upon intradermal administration, the autologous HNSCC DNA-transfected semi-allogeneic fibroblasts MRC-5 vaccine expresses HNSCC tumor-associated antigens (TAAs), which may activate the immune system to induce a cytotoxic T-lymphocyte (CTL) response against HNSCC cells. The MRC-5 cell line, established in 1966, is a human diploid lung fibroblast cell line derived from the human lung tissue of a 14-week-old male fetus." @default.
- NCIT_C117725 NCIT_NHC0 "C117725" @default.
- NCIT_C117725 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C117725 NCIT_P108 "Autologous HNSCC DNA-transfected Semi-allogeneic Fibroblasts MRC-5 Vaccine" @default.
- NCIT_C117725 NCIT_P208 "CL474120" @default.
- NCIT_C117725 NCIT_P329 "763738" @default.
- NCIT_C117725 NCIT_P330 "763738" @default.
- NCIT_C117725 NCIT_P399 "763738" @default.
- NCIT_C117725 normalizedInformationContent "100" @default.
- NCIT_C117725 referenceCount "1" @default.
- NCIT_C117725 hasExactSynonym "Autologous HNSCC DNA-transfected Semi-allogeneic Fibroblasts MRC-5 Vaccine" @default.
- NCIT_C117725 inSubset NCIT_C128784 @default.
- NCIT_C117725 inSubset NCIT_C176424 @default.
- NCIT_C117725 type Class @default.
- NCIT_C117725 isDefinedBy ncit.owl @default.
- NCIT_C117725 label "Autologous HNSCC DNA-transfected Semi-allogeneic Fibroblasts MRC-5 Vaccine" @default.
- NCIT_C117725 subClassOf NCIT_C117725 @default.
- NCIT_C117725 subClassOf NCIT_C129820 @default.
- NCIT_C117725 subClassOf NCIT_C1663 @default.
- NCIT_C117725 subClassOf NCIT_C1908 @default.
- NCIT_C117725 subClassOf NCIT_C1909 @default.
- NCIT_C117725 subClassOf NCIT_C1983 @default.
- NCIT_C117725 subClassOf NCIT_C2341 @default.
- NCIT_C117725 subClassOf NCIT_C274 @default.
- NCIT_C117725 subClassOf NCIT_C307 @default.
- NCIT_C117725 subClassOf NCIT_C308 @default.
- NCIT_C117725 subClassOf NCIT_C923 @default.