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- NCIT_C117726 IAO_0000115 "A recombinant monoclonal antibody against human epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Upon administration, anti-EGFR monoclonal antibody SCT200 targets EGFR, prevents the activation and subsequent dimerization of this receptor and inhibits both EGFR-mediated signal transduction and cellular proliferation of EGFR-expressing tumor cells. In addition, SCT200 may induce antibody-dependent cell-mediated cytotoxicity (ADCC) against EGFR-expressing tumor cells. EGFR, a member of the epidermal growth factor receptor family, is overexpressed on the cell surfaces of various solid tumors." @default.
- NCIT_C117726 NCIT_A32 NCIT_C1909 @default.
- NCIT_C117726 NCIT_A7 NCIT_C17068 @default.
- NCIT_C117726 NCIT_NHC0 "C117726" @default.
- NCIT_C117726 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C117726 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C117726 NCIT_P108 "Anti-EGFR Monoclonal Antibody SCT200" @default.
- NCIT_C117726 NCIT_P208 "CL474121" @default.
- NCIT_C117726 NCIT_P322 "GDC" @default.
- NCIT_C117726 NCIT_P329 "763740" @default.
- NCIT_C117726 NCIT_P330 "763740" @default.
- NCIT_C117726 NCIT_P375 "Anti-EGFR Monoclonal Antibody SCT200" @default.
- NCIT_C117726 NCIT_P399 "763740" @default.
- NCIT_C117726 NCIT_R124 NCIT_C17710 @default.
- NCIT_C117726 NCIT_R124 NCIT_C17828 @default.
- NCIT_C117726 NCIT_R124 NCIT_C18219 @default.
- NCIT_C117726 NCIT_R124 NCIT_C19986 @default.
- NCIT_C117726 NCIT_R124 NCIT_C40474 @default.
- NCIT_C117726 normalizedInformationContent "100" @default.
- NCIT_C117726 referenceCount "1" @default.
- NCIT_C117726 hasExactSynonym "Anti-EGFR Monoclonal Antibody SCT200" @default.
- NCIT_C117726 hasExactSynonym "SCT200" @default.
- NCIT_C117726 inSubset NCIT_C128784 @default.
- NCIT_C117726 inSubset NCIT_C157711 @default.
- NCIT_C117726 inSubset NCIT_C157712 @default.
- NCIT_C117726 inSubset NCIT_C176424 @default.
- NCIT_C117726 inSubset NCIT_C177537 @default.
- NCIT_C117726 type Class @default.
- NCIT_C117726 isDefinedBy ncit.owl @default.
- NCIT_C117726 label "Anti-EGFR Monoclonal Antibody SCT200" @default.
- NCIT_C117726 subClassOf NCIT_C117726 @default.
- NCIT_C117726 subClassOf NCIT_C129821 @default.
- NCIT_C117726 subClassOf NCIT_C129822 @default.
- NCIT_C117726 subClassOf NCIT_C133878 @default.
- NCIT_C117726 subClassOf NCIT_C163758 @default.
- NCIT_C117726 subClassOf NCIT_C163952 @default.
- NCIT_C117726 subClassOf NCIT_C1908 @default.
- NCIT_C117726 subClassOf NCIT_C1909 @default.
- NCIT_C117726 subClassOf NCIT_C20401 @default.
- NCIT_C117726 subClassOf NCIT_C274 @default.
- NCIT_C117726 subClassOf NCIT_C307 @default.
- NCIT_C117726 subClassOf NCIT_C308 @default.