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- NCIT_C117729 IAO_0000115 "A preparation of autologous peripheral blood T-lymphocytes (PBTLs) that have been genetically modified to express a chimeric antigen receptor (CAR) specific for the B-cell maturation antigen (BCMA), with potential immunostimulating and antineoplastic activities. Upon administration, idecabtagene vicleucel specifically recognizes and kills BCMA-expressing tumor cells. BCMA, a tumor-specific antigen and a receptor for both a proliferation-inducing ligand (APRIL) and B-cell activating factor (BAFF), is a member of the tumor necrosis factor receptor superfamily (TNFRSF) and plays a key role in plasma survival; it is found on the surfaces of plasma cells and overexpressed on malignant plasma cells." @default.
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- NCIT_C117729 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C117729 NCIT_P107 "Idecabtagene Vicleucel" @default.
- NCIT_C117729 NCIT_P108 "Idecabtagene Vicleucel" @default.
- NCIT_C117729 NCIT_P208 "CL474124" @default.
- NCIT_C117729 NCIT_P302 "adult patients with multiple myeloma" @default.
- NCIT_C117729 NCIT_P319 "8PX1X7UG4D" @default.
- NCIT_C117729 NCIT_P322 "CTRP" @default.
- NCIT_C117729 NCIT_P322 "FDA" @default.
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- NCIT_C117729 NCIT_P329 "763837" @default.
- NCIT_C117729 NCIT_P330 "763837" @default.
- NCIT_C117729 NCIT_P375 "Idecabtagene Vicleucel" @default.
- NCIT_C117729 NCIT_P399 "763837" @default.
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- NCIT_C117729 NCIT_R72 NCIT_C104083 @default.
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- NCIT_C117729 NCIT_R72 NCIT_C12476 @default.
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- NCIT_C117729 NCIT_R72 NCIT_C33061 @default.
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- NCIT_C117729 NCIT_R72 NCIT_C38439 @default.
- NCIT_C117729 NCIT_R72 NCIT_C39567 @default.
- NCIT_C117729 NCIT_R72 NCIT_C39568 @default.
- NCIT_C117729 normalizedInformationContent "100" @default.
- NCIT_C117729 referenceCount "1" @default.
- NCIT_C117729 hasExactSynonym "Abecma" @default.
- NCIT_C117729 hasExactSynonym "Anti-BCMA CAR T Cells BB2121" @default.
- NCIT_C117729 hasExactSynonym "Anti-BCMA-CAR-transduced T Cells BB2121" @default.
- NCIT_C117729 hasExactSynonym "BB2121" @default.
- NCIT_C117729 hasExactSynonym "BCMA-specific CAR-expressing T Lymphocytes BB2121" @default.
- NCIT_C117729 hasExactSynonym "IDECABTAGENE VICLEUCEL" @default.
- NCIT_C117729 hasExactSynonym "Ide-cel" @default.
- NCIT_C117729 hasExactSynonym "Idecabtagene Vicleucel" @default.
- NCIT_C117729 inSubset NCIT_C116977 @default.
- NCIT_C117729 inSubset NCIT_C116978 @default.
- NCIT_C117729 inSubset NCIT_C128784 @default.
- NCIT_C117729 inSubset NCIT_C157711 @default.
- NCIT_C117729 inSubset NCIT_C157712 @default.
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- NCIT_C117729 inSubset NCIT_C177537 @default.
- NCIT_C117729 inSubset NCIT_C63923 @default.
- NCIT_C117729 type Class @default.
- NCIT_C117729 isDefinedBy ncit.owl @default.
- NCIT_C117729 label "Idecabtagene Vicleucel" @default.
- NCIT_C117729 subClassOf NCIT_C117729 @default.
- NCIT_C117729 subClassOf NCIT_C129820 @default.
- NCIT_C117729 subClassOf NCIT_C129821 @default.
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- NCIT_C117729 subClassOf NCIT_C1908 @default.
- NCIT_C117729 subClassOf NCIT_C1909 @default.
- NCIT_C117729 subClassOf NCIT_C1962 @default.
- NCIT_C117729 subClassOf NCIT_C200766 @default.
- NCIT_C117729 subClassOf NCIT_C274 @default.
- NCIT_C117729 subClassOf NCIT_C28681 @default.
- NCIT_C117729 subClassOf NCIT_C307 @default.
- NCIT_C117729 subClassOf NCIT_C308 @default.