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- NCIT_C1180 IAO_0000115 "A recombinant 26.0 kDa protein, containing 227 amino acid residues, a member of the cytokine family and growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposi's sarcoma cells, oncostatin M (OSM) can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposi's sarcoma cells, but inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells." @default.
- NCIT_C1180 NCIT_NHC0 "C1180" @default.
- NCIT_C1180 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C1180 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1180 NCIT_P108 "Recombinant Oncostatin M" @default.
- NCIT_C1180 NCIT_P207 "C3887694" @default.
- NCIT_C1180 NCIT_P210 "106956-32-5" @default.
- NCIT_C1180 NCIT_P366 "Therapeutic_Oncostatin_M" @default.
- NCIT_C1180 normalizedInformationContent "100" @default.
- NCIT_C1180 referenceCount "1" @default.
- NCIT_C1180 hasExactSynonym "OSM" @default.
- NCIT_C1180 hasExactSynonym "Recombinant Oncostatin M" @default.
- NCIT_C1180 type Class @default.
- NCIT_C1180 isDefinedBy ncit.owl @default.
- NCIT_C1180 label "Recombinant Oncostatin M" @default.
- NCIT_C1180 subClassOf NCIT_C1180 @default.
- NCIT_C1180 subClassOf NCIT_C1283 @default.
- NCIT_C1180 subClassOf NCIT_C1908 @default.
- NCIT_C1180 subClassOf NCIT_C1909 @default.
- NCIT_C1180 subClassOf NCIT_C307 @default.
- NCIT_C1180 subClassOf NCIT_C308 @default.