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- NCIT_C118185 IAO_0000115 "C4d (380 aa, ~41 kDa) is a fragment of complement component-4. This protein plays a role in the regulation of the classical and lectin complement pathways. It may be a biomarker for complement activation during antibody-mediated rejection of transplants and in other pathological conditions." @default.
- NCIT_C118185 NCIT_A13 NCIT_C128857 @default.
- NCIT_C118185 NCIT_A13 NCIT_C128859 @default.
- NCIT_C118185 NCIT_A13 NCIT_C128863 @default.
- NCIT_C118185 NCIT_NHC0 "C118185" @default.
- NCIT_C118185 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C118185 NCIT_P107 "C4d" @default.
- NCIT_C118185 NCIT_P108 "C4d" @default.
- NCIT_C118185 NCIT_P207 "C0056195" @default.
- NCIT_C118185 NCIT_P322 "CTRP" @default.
- NCIT_C118185 NCIT_P98 "Human complement component C4 is polymorphic at two loci, C4A and C4B, thus C4d is encoded by both of these genes. Both forms of complement component-4 can be cleaved to generate C4 alpha chain and C4 beta chain. The alpha chain can be further processed to release C4a anaphylatoxin and C4b. C4b is membrane bound and recruits C2a to form the C4b2a form of the C3-convertase in the classical complement pathway. To deactivate the C3-convertase, C4b is cleaved further to form the inactive fragments C4c and C4d. C4d remains bound to the surface of the endothelium." @default.
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- NCIT_C118185 normalizedInformationContent "100" @default.
- NCIT_C118185 referenceCount "1" @default.
- NCIT_C118185 hasExactSynonym "C4D" @default.
- NCIT_C118185 hasExactSynonym "C4d" @default.
- NCIT_C118185 hasExactSynonym "Complement C4d" @default.
- NCIT_C118185 hasExactSynonym "Complement Component 4d" @default.
- NCIT_C118185 hasExactSynonym "Complement Component-4d" @default.
- NCIT_C118185 inSubset NCIT_C116977 @default.
- NCIT_C118185 inSubset NCIT_C142799 @default.
- NCIT_C118185 inSubset NCIT_C142800 @default.
- NCIT_C118185 type Class @default.
- NCIT_C118185 isDefinedBy ncit.owl @default.
- NCIT_C118185 label "C4d" @default.
- NCIT_C118185 subClassOf B0cfa07eba26c73cabb8940e36cfb7ab2 @default.
- NCIT_C118185 subClassOf B0ec17534a494489460f27fa5333a2860 @default.
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