Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C118281> ?p ?o ?g. }
Showing items 1 to 44 of
44
with 100 items per page.
- NCIT_C118281 IAO_0000115 "A monoclonal antibody (MoAb) against human epidermal growth factor receptor (EGFR) and human hepatocyte growth factor receptor (HGFR or c-Met), with potential antineoplastic activity. Upon administration, anti-Met/EGFR MoAb LY3164530 targets and prevents the activation of EGFR and c-Met. This leads to a downstream inhibition of EGFR/c-Met-mediated signal transduction pathways, and prevents cellular proliferation in tumor cells overexpressing EGFR and c-Met. EGFR, a member of the epidermal growth factor family of extracellular protein ligands, may be overexpressed on the cell surface of various solid tumor cell types. c-Met, a receptor tyrosine kinase overexpressed or mutated in many tumor cell types, plays a key role in cancer cell growth, survival, angiogenesis, invasion, and metastasis." @default.
- NCIT_C118281 NCIT_A32 NCIT_C1909 @default.
- NCIT_C118281 NCIT_NHC0 "C118281" @default.
- NCIT_C118281 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C118281 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C118281 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C118281 NCIT_P108 "Anti-Met/EGFR Monoclonal Antibody LY3164530" @default.
- NCIT_C118281 NCIT_P208 "CL474133" @default.
- NCIT_C118281 NCIT_P210 "2069210-01-9" @default.
- NCIT_C118281 NCIT_P319 "K85WE44TZ7" @default.
- NCIT_C118281 NCIT_P322 "FDA" @default.
- NCIT_C118281 NCIT_P322 "GDC" @default.
- NCIT_C118281 NCIT_P329 "764231" @default.
- NCIT_C118281 NCIT_P330 "764231" @default.
- NCIT_C118281 NCIT_P375 "Anti-Met/EGFR Monoclonal Antibody LY3164530" @default.
- NCIT_C118281 NCIT_P399 "764231" @default.
- NCIT_C118281 NCIT_R124 NCIT_C17710 @default.
- NCIT_C118281 NCIT_R124 NCIT_C17828 @default.
- NCIT_C118281 NCIT_R124 NCIT_C18219 @default.
- NCIT_C118281 NCIT_R124 NCIT_C19986 @default.
- NCIT_C118281 NCIT_R124 NCIT_C40474 @default.
- NCIT_C118281 normalizedInformationContent "100" @default.
- NCIT_C118281 referenceCount "1" @default.
- NCIT_C118281 hasExactSynonym "Anti-Met/EGFR Monoclonal Antibody LY3164530" @default.
- NCIT_C118281 hasExactSynonym "LY-3164530" @default.
- NCIT_C118281 hasExactSynonym "LY3164530" @default.
- NCIT_C118281 inSubset NCIT_C128784 @default.
- NCIT_C118281 inSubset NCIT_C157711 @default.
- NCIT_C118281 inSubset NCIT_C157712 @default.
- NCIT_C118281 inSubset NCIT_C176424 @default.
- NCIT_C118281 inSubset NCIT_C177537 @default.
- NCIT_C118281 inSubset NCIT_C63923 @default.
- NCIT_C118281 type Class @default.
- NCIT_C118281 isDefinedBy ncit.owl @default.
- NCIT_C118281 label "Anti-Met/EGFR Monoclonal Antibody LY3164530" @default.
- NCIT_C118281 subClassOf NCIT_C118281 @default.
- NCIT_C118281 subClassOf NCIT_C129821 @default.
- NCIT_C118281 subClassOf NCIT_C129822 @default.
- NCIT_C118281 subClassOf NCIT_C1908 @default.
- NCIT_C118281 subClassOf NCIT_C1909 @default.
- NCIT_C118281 subClassOf NCIT_C20401 @default.
- NCIT_C118281 subClassOf NCIT_C274 @default.
- NCIT_C118281 subClassOf NCIT_C307 @default.
- NCIT_C118281 subClassOf NCIT_C308 @default.