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- NCIT_C118284 IAO_0000115 "A humanized monoclonal antibody against the extracellular domain of the human receptor tyrosine kinase-like orphan receptor 1 (ROR1), with potential antineoplastic activity. Upon administration, zilovertamab binds to ROR1 and blocks ROR1-mediated signaling. This prevents tumor cell proliferation in cancer cells overexpressing ROR1. ROR1, also known as neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), is normally expressed during embryogenesis. It is overexpressed in certain leukemias and solid tumors, but minimally expressed in healthy cells." @default.
- NCIT_C118284 NCIT_A32 NCIT_C1909 @default.
- NCIT_C118284 NCIT_A7 NCIT_C29879 @default.
- NCIT_C118284 NCIT_NHC0 "C118284" @default.
- NCIT_C118284 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C118284 NCIT_P107 "Zilovertamab" @default.
- NCIT_C118284 NCIT_P108 "Zilovertamab" @default.
- NCIT_C118284 NCIT_P208 "CL474136" @default.
- NCIT_C118284 NCIT_P210 "2485779-13-1" @default.
- NCIT_C118284 NCIT_P319 "FEH7RQ7B3J" @default.
- NCIT_C118284 NCIT_P322 "CTRP" @default.
- NCIT_C118284 NCIT_P322 "FDA" @default.
- NCIT_C118284 NCIT_P322 "GDC" @default.
- NCIT_C118284 NCIT_P329 "764235" @default.
- NCIT_C118284 NCIT_P330 "764235" @default.
- NCIT_C118284 NCIT_P375 "Cirmtuzumab" @default.
- NCIT_C118284 NCIT_P399 "764235" @default.
- NCIT_C118284 NCIT_R124 NCIT_C17710 @default.
- NCIT_C118284 NCIT_R124 NCIT_C17828 @default.
- NCIT_C118284 NCIT_R124 NCIT_C18219 @default.
- NCIT_C118284 NCIT_R124 NCIT_C19986 @default.
- NCIT_C118284 NCIT_R124 NCIT_C40474 @default.
- NCIT_C118284 normalizedInformationContent "100" @default.
- NCIT_C118284 referenceCount "1" @default.
- NCIT_C118284 hasExactSynonym "Cirmtuzumab" @default.
- NCIT_C118284 hasExactSynonym "UC-961" @default.
- NCIT_C118284 hasExactSynonym "ZILOVERTAMAB" @default.
- NCIT_C118284 hasExactSynonym "Zilovertamab" @default.
- NCIT_C118284 inSubset NCIT_C116977 @default.
- NCIT_C118284 inSubset NCIT_C116978 @default.
- NCIT_C118284 inSubset NCIT_C128784 @default.
- NCIT_C118284 inSubset NCIT_C157711 @default.
- NCIT_C118284 inSubset NCIT_C157712 @default.
- NCIT_C118284 inSubset NCIT_C176424 @default.
- NCIT_C118284 inSubset NCIT_C177537 @default.
- NCIT_C118284 inSubset NCIT_C63923 @default.
- NCIT_C118284 type Class @default.
- NCIT_C118284 isDefinedBy ncit.owl @default.
- NCIT_C118284 label "Zilovertamab" @default.
- NCIT_C118284 subClassOf NCIT_C118284 @default.
- NCIT_C118284 subClassOf NCIT_C129821 @default.
- NCIT_C118284 subClassOf NCIT_C129822 @default.
- NCIT_C118284 subClassOf NCIT_C163758 @default.
- NCIT_C118284 subClassOf NCIT_C1908 @default.
- NCIT_C118284 subClassOf NCIT_C1909 @default.
- NCIT_C118284 subClassOf NCIT_C199675 @default.
- NCIT_C118284 subClassOf NCIT_C20401 @default.
- NCIT_C118284 subClassOf NCIT_C274 @default.
- NCIT_C118284 subClassOf NCIT_C307 @default.
- NCIT_C118284 subClassOf NCIT_C308 @default.