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- NCIT_C118369 IAO_0000115 "A foam-based formulation composed of the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic, with antimicrobial activity. Upon topical application of the foam, doxycycline reversibly binds to the bacterial 30S ribosomal subunit, and blocks the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of bacterial protein synthesis. This may prevent both the bacterial infections and the subsequent infections and pain associated with epidermal growth factor receptor inhibitor (EGFRI)-induced acne-like rash." @default.
- NCIT_C118369 NCIT_NHC0 "C118369" @default.
- NCIT_C118369 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C118369 NCIT_P108 "Doxycycline Hyclate Foam" @default.
- NCIT_C118369 NCIT_P207 "C3899335" @default.
- NCIT_C118369 NCIT_P329 "764771" @default.
- NCIT_C118369 NCIT_P330 "764771" @default.
- NCIT_C118369 NCIT_P399 "764771" @default.
- NCIT_C118369 normalizedInformationContent "100" @default.
- NCIT_C118369 referenceCount "1" @default.
- NCIT_C118369 hasExactSynonym "Doxycycline Hyclate Foam" @default.
- NCIT_C118369 hasExactSynonym "FDX104 Antibiotic Foam" @default.
- NCIT_C118369 hasExactSynonym "FDX104" @default.
- NCIT_C118369 inSubset NCIT_C176424 @default.
- NCIT_C118369 type Class @default.
- NCIT_C118369 isDefinedBy ncit.owl @default.
- NCIT_C118369 label "Doxycycline Hyclate Foam" @default.
- NCIT_C118369 subClassOf NCIT_C118369 @default.
- NCIT_C118369 subClassOf NCIT_C1595 @default.
- NCIT_C118369 subClassOf NCIT_C1908 @default.
- NCIT_C118369 subClassOf NCIT_C1909 @default.
- NCIT_C118369 subClassOf NCIT_C254 @default.
- NCIT_C118369 subClassOf NCIT_C258 @default.
- NCIT_C118369 subClassOf NCIT_C784 @default.