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- NCIT_C118575 IAO_0000115 "An imaging agent containing a plectin-1 (Plec1; plectin) targeting peptide (PTP), with potential use for the detection of Plec1-expressing tumor cells using single-photon emission computed tomography (SPECT). Upon administration, the Plec1 targeting agent PTP-01 specifically targets and binds to Plec1 on Plec1-expressing cancer cells. Upon SPECT imaging, the Plec1-expressing cancer cells can be visualized. Plec1, a pro-tumorigenic protein, is normally found inside the cytoplasm of healthy cells but is only selectively expressed on the cell surface of various cancer cells and plays an important role in cancer cell proliferation, migration and invasion." @default.
- NCIT_C118575 NCIT_NHC0 "C118575" @default.
- NCIT_C118575 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C118575 NCIT_P106 "Organic Chemical" @default.
- NCIT_C118575 NCIT_P107 "Plectin-1 Targeting Agent PTP-01" @default.
- NCIT_C118575 NCIT_P108 "Plectin-1 Targeting Agent PTP-01" @default.
- NCIT_C118575 NCIT_P208 "CL471753" @default.
- NCIT_C118575 NCIT_P322 "CTRP" @default.
- NCIT_C118575 NCIT_P399 "754308" @default.
- NCIT_C118575 normalizedInformationContent "100" @default.
- NCIT_C118575 referenceCount "1" @default.
- NCIT_C118575 hasExactSynonym "PTP-01" @default.
- NCIT_C118575 hasExactSynonym "Plectin-1 Targeting Agent PTP-01" @default.
- NCIT_C118575 inSubset NCIT_C116977 @default.
- NCIT_C118575 inSubset NCIT_C116978 @default.
- NCIT_C118575 inSubset NCIT_C176424 @default.
- NCIT_C118575 type Class @default.
- NCIT_C118575 isDefinedBy ncit.owl @default.
- NCIT_C118575 label "Plectin-1 Targeting Agent PTP-01" @default.
- NCIT_C118575 subClassOf NCIT_C118575 @default.
- NCIT_C118575 subClassOf NCIT_C1908 @default.
- NCIT_C118575 subClassOf NCIT_C1966 @default.
- NCIT_C118575 subClassOf NCIT_C45678 @default.
- NCIT_C118575 subClassOf NCIT_C802 @default.