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- NCIT_C1186 IAO_0000115 "A chloroethylnitrosourea compound and an alkylating agent with antineoplastic property. PCNU inhibits DNA synthesis by alkylating DNA and causing DNA cross links, thereby inducing apoptosis. In addition, this agent may be associated with pulmonary, hepatic, and hematologic toxicities. Unlike other nitrosoureas, PCNU has strong alkylating while weak carbamoylating activity." @default.
- NCIT_C1186 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1186 NCIT_NHC0 "C1186" @default.
- NCIT_C1186 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1186 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1186 NCIT_P108 "PCNU" @default.
- NCIT_C1186 NCIT_P175 "95466" @default.
- NCIT_C1186 NCIT_P207 "C0070165" @default.
- NCIT_C1186 NCIT_P210 "13909-02-9" @default.
- NCIT_C1186 NCIT_P319 "AZW59V4Q3B" @default.
- NCIT_C1186 NCIT_P322 "FDA" @default.
- NCIT_C1186 NCIT_P322 "GDC" @default.
- NCIT_C1186 NCIT_P329 "39549" @default.
- NCIT_C1186 NCIT_P330 "39549" @default.
- NCIT_C1186 NCIT_P366 "PCNU" @default.
- NCIT_C1186 NCIT_P375 "PCNU" @default.
- NCIT_C1186 NCIT_P399 "39549" @default.
- NCIT_C1186 normalizedInformationContent "100" @default.
- NCIT_C1186 referenceCount "1" @default.
- NCIT_C1186 hasExactSynonym "1-(2-CHLOROETHYL)-3-(2,6-DIOXO-3-PIPERIDYL)-1-NITROSOUREA" @default.
- NCIT_C1186 hasExactSynonym "1-(2-Chloroethyl)-3-(2,6-Dioxo-3-Piperidyl)-1-Nitrourea" @default.
- NCIT_C1186 hasExactSynonym "PCNU" @default.
- NCIT_C1186 hasExactSynonym "Urea, N-(2-chloroethyl)-N'-(2,6-dioxo-3-piperidinyl)-N-nitroso-" @default.
- NCIT_C1186 inSubset NCIT_C128784 @default.
- NCIT_C1186 inSubset NCIT_C157711 @default.
- NCIT_C1186 inSubset NCIT_C157712 @default.
- NCIT_C1186 inSubset NCIT_C176424 @default.
- NCIT_C1186 inSubset NCIT_C177537 @default.
- NCIT_C1186 inSubset NCIT_C63923 @default.
- NCIT_C1186 type Class @default.
- NCIT_C1186 isDefinedBy ncit.owl @default.
- NCIT_C1186 label "PCNU" @default.
- NCIT_C1186 subClassOf NCIT_C1186 @default.
- NCIT_C1186 subClassOf NCIT_C1590 @default.
- NCIT_C1186 subClassOf NCIT_C186664 @default.
- NCIT_C1186 subClassOf NCIT_C1908 @default.
- NCIT_C1186 subClassOf NCIT_C1909 @default.
- NCIT_C1186 subClassOf NCIT_C274 @default.
- NCIT_C1186 subClassOf NCIT_C2842 @default.
- NCIT_C1186 subClassOf NCIT_C699 @default.