Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C118621> ?p ?o ?g. }
Showing items 1 to 38 of
38
with 100 items per page.
- NCIT_C118621 IAO_0000115 "A nanodispersion containing the benzoquinone ubidecarenone (coenzyme Q10), with potential protective, antioxidant and antineoplastic activities. Upon administration, ubidecarenone nanodispersion BPM31510 modulates tumor cell metabolism and causes an anti-Warburg effect by inducing a shift from lactate dependency towards mitochondrial oxidative phosphorylation, and induces tumor cell apoptosis. This inhibits tumor cell proliferation. BPM 31510 also induces the activation and maturation of T-lymphocytes, and changes the surface expression of certain immune checkpoint modulators. In addition, as an antioxidant, ubidecarenone protects against cell damage, by preventing both the peroxidation of lipid membranes and the oxidation of LDL-cholesterol. Ubidecarenone is an essential coenzyme for mitochondrial enzyme complexes involved in oxidative phosphorylation and the production of adenosine triphosphate (ATP)." @default.
- NCIT_C118621 NCIT_A32 NCIT_C1909 @default.
- NCIT_C118621 NCIT_NHC0 "C118621" @default.
- NCIT_C118621 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C118621 NCIT_P107 "Ubidecarenone Injectable Nanosuspension" @default.
- NCIT_C118621 NCIT_P108 "Ubidecarenone Nanodispersion BPM31510n" @default.
- NCIT_C118621 NCIT_P207 "C3897258" @default.
- NCIT_C118621 NCIT_P322 "CTRP" @default.
- NCIT_C118621 NCIT_P322 "GDC" @default.
- NCIT_C118621 NCIT_P329 "791848" @default.
- NCIT_C118621 NCIT_P330 "791848" @default.
- NCIT_C118621 NCIT_P375 "Ubidecarenone Nanodispersion BPM31510n" @default.
- NCIT_C118621 NCIT_P399 "791848" @default.
- NCIT_C118621 normalizedInformationContent "100" @default.
- NCIT_C118621 referenceCount "1" @default.
- NCIT_C118621 hasExactSynonym "BP31510" @default.
- NCIT_C118621 hasExactSynonym "Coenzyme Q10 Injectable Nanosuspension" @default.
- NCIT_C118621 hasExactSynonym "Ubidecarenone Injectable Nanosuspension" @default.
- NCIT_C118621 hasExactSynonym "Ubidecarenone Nanodispersion BPM31510n" @default.
- NCIT_C118621 hasExactSynonym "Ubiquinone Injectable Nanosuspension" @default.
- NCIT_C118621 inSubset NCIT_C116977 @default.
- NCIT_C118621 inSubset NCIT_C116978 @default.
- NCIT_C118621 inSubset NCIT_C128784 @default.
- NCIT_C118621 inSubset NCIT_C157711 @default.
- NCIT_C118621 inSubset NCIT_C157712 @default.
- NCIT_C118621 inSubset NCIT_C176424 @default.
- NCIT_C118621 inSubset NCIT_C177537 @default.
- NCIT_C118621 type Class @default.
- NCIT_C118621 isDefinedBy ncit.owl @default.
- NCIT_C118621 label "Ubidecarenone Nanodispersion BPM31510n" @default.
- NCIT_C118621 subClassOf NCIT_C118621 @default.
- NCIT_C118621 subClassOf NCIT_C129820 @default.
- NCIT_C118621 subClassOf NCIT_C1908 @default.
- NCIT_C118621 subClassOf NCIT_C1909 @default.
- NCIT_C118621 subClassOf NCIT_C26170 @default.
- NCIT_C118621 subClassOf NCIT_C274 @default.
- NCIT_C118621 subClassOf NCIT_C275 @default.
- NCIT_C118621 subClassOf NCIT_C308 @default.