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- NCIT_C118949 IAO_0000115 "A population of allogeneic, cytokine-differentiated, highly lytic natural killer (NK) cells derived from CD34+ cells isolated from human umbilical cord blood (UCB) with potential cytotoxic activity. CD34+ hematopoietic stem cells (HSC) are isolated from human UCB mononuclear cells, differentiated into mature, highly lytic, CD3- CD56+ NK cells, by a specific combination of cytokines that includes stem cell factor (SCF), fms-related tyrosine kinase 3 ligand (Flt3-L), interleukin-15 (IL-15) and insulin-like growth factor-1 (IGF-1), and expanded ex vivo. Upon administration, the UCB-derived NK cells may lyse cancer cells." @default.
- NCIT_C118949 NCIT_NHC0 "C118949" @default.
- NCIT_C118949 NCIT_P106 "Cell" @default.
- NCIT_C118949 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C118949 NCIT_P108 "Umbilical Cord Blood-derived Natural Killer Cells" @default.
- NCIT_C118949 NCIT_P207 "C3897252" @default.
- NCIT_C118949 NCIT_P329 "766363" @default.
- NCIT_C118949 NCIT_P330 "766363" @default.
- NCIT_C118949 NCIT_P399 "766363" @default.
- NCIT_C118949 normalizedInformationContent "100" @default.
- NCIT_C118949 referenceCount "1" @default.
- NCIT_C118949 hasExactSynonym "Cord Blood NK Cells" @default.
- NCIT_C118949 hasExactSynonym "Umbilical Cord Blood-derived NK Cells" @default.
- NCIT_C118949 hasExactSynonym "Umbilical Cord Blood-derived Natural Killer Cells" @default.
- NCIT_C118949 inSubset NCIT_C128784 @default.
- NCIT_C118949 inSubset NCIT_C176424 @default.
- NCIT_C118949 type Class @default.
- NCIT_C118949 isDefinedBy ncit.owl @default.
- NCIT_C118949 label "Umbilical Cord Blood-derived Natural Killer Cells" @default.
- NCIT_C118949 subClassOf NCIT_C118949 @default.
- NCIT_C118949 subClassOf NCIT_C129820 @default.
- NCIT_C118949 subClassOf NCIT_C129821 @default.
- NCIT_C118949 subClassOf NCIT_C129826 @default.
- NCIT_C118949 subClassOf NCIT_C142078 @default.
- NCIT_C118949 subClassOf NCIT_C1908 @default.
- NCIT_C118949 subClassOf NCIT_C1909 @default.
- NCIT_C118949 subClassOf NCIT_C201545 @default.
- NCIT_C118949 subClassOf NCIT_C274 @default.
- NCIT_C118949 subClassOf NCIT_C28676 @default.
- NCIT_C118949 subClassOf NCIT_C307 @default.
- NCIT_C118949 subClassOf NCIT_C308 @default.