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- NCIT_C1192 IAO_0000115 "A phospholipid that is a component of the plasma membrane with signal transduction inducing activity. Phosphatidylinositol 4,5-bisphosphate (PIP2) is an intermediate that can be converted into either the second messenger signaling molecules, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), or phosphatidylinositol (3,4,5)-trisphosphate (PtdIns(3,4,5)P3; PIP3). Both PIP2 and PIP3 can act as docking phospholipids, which recruit signaling proteins to the plasma membrane and promotes the activation of several signaling cascades." @default.
- NCIT_C1192 NCIT_NHC0 "C1192" @default.
- NCIT_C1192 NCIT_P106 "Biologically Active Substance" @default.
- NCIT_C1192 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1192 NCIT_P108 "Phosphatidylinositol 4,5-bisphosphate" @default.
- NCIT_C1192 NCIT_P207 "C0070798" @default.
- NCIT_C1192 NCIT_P366 "Phosphatidylinositol_4_5-bisphosphate" @default.
- NCIT_C1192 NCIT_P368 "CHEBI:18348" @default.
- NCIT_C1192 normalizedInformationContent "100" @default.
- NCIT_C1192 referenceCount "1" @default.
- NCIT_C1192 hasExactSynonym "1,2-Diacyl-sn-Glycero-3-Phospho-(1'-myo-Inositol-4',5'-Bisphosphate)" @default.
- NCIT_C1192 hasExactSynonym "1-O-(3-sn-Phosphatidyl)-1D-myo-Inositol 4,5-Bis(Dihydrogen Phosphate)" @default.
- NCIT_C1192 hasExactSynonym "1-Phosphatidyl-1D-myo-Inositol 4,5-Bisphosphate" @default.
- NCIT_C1192 hasExactSynonym "1-Phosphatidyl-D-myo-Inositol 4,5-Bisphosphate" @default.
- NCIT_C1192 hasExactSynonym "PIP2" @default.
- NCIT_C1192 hasExactSynonym "PIPP" @default.
- NCIT_C1192 hasExactSynonym "Phosphatidyl-myo-Inositol 4,5-Bisphosphate" @default.
- NCIT_C1192 hasExactSynonym "Phosphatidylinositol 4,5-Diphosphate" @default.
- NCIT_C1192 hasExactSynonym "Phosphatidylinositol 4,5-bisphosphate" @default.
- NCIT_C1192 hasExactSynonym "PtdIns(4,5)P2" @default.
- NCIT_C1192 hasExactSynonym "PtsIns-4,5-P2" @default.
- NCIT_C1192 type Class @default.
- NCIT_C1192 isDefinedBy ncit.owl @default.
- NCIT_C1192 label "Phosphatidylinositol 4,5-bisphosphate" @default.
- NCIT_C1192 subClassOf NCIT_C1192 @default.
- NCIT_C1192 subClassOf NCIT_C1899 @default.
- NCIT_C1192 subClassOf NCIT_C1903 @default.
- NCIT_C1192 subClassOf NCIT_C1908 @default.
- NCIT_C1192 subClassOf NCIT_C1913 @default.
- NCIT_C1192 subClassOf NCIT_C1929 @default.
- NCIT_C1192 subClassOf NCIT_C1930 @default.
- NCIT_C1192 subClassOf NCIT_C1949 @default.
- NCIT_C1192 subClassOf NCIT_C2317 @default.
- NCIT_C1192 subClassOf NCIT_C54060 @default.
- NCIT_C1192 subClassOf NCIT_C616 @default.
- NCIT_C1192 subClassOf NCIT_C68340 @default.
- NCIT_C1192 subClassOf NCIT_C70568 @default.
- NCIT_C1192 subClassOf NCIT_C718 @default.