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- NCIT_C1196 IAO_0000115 "A 2-nitroimidazole with hypoxic selectivity and potential radiosensitizing activities. Pimonidazole is reduced in hypoxic environments such as those found in tumors. In hypoxic cells, reduced pimonidazole binds to thiol-containing proteins. The resulting complexes accumulate in hypoxic tumors, thereby depleting radioprotective thiol compounds and sensitizing tumor cells to be more susceptible for radiation treatment." @default.
- NCIT_C1196 NCIT_A5 NCIT_C29366 @default.
- NCIT_C1196 NCIT_NHC0 "C1196" @default.
- NCIT_C1196 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C1196 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1196 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1196 NCIT_P108 "Pimonidazole" @default.
- NCIT_C1196 NCIT_P175 "380540" @default.
- NCIT_C1196 NCIT_P207 "C0071072" @default.
- NCIT_C1196 NCIT_P210 "70132-51-3" @default.
- NCIT_C1196 NCIT_P319 "46JO4D76R2" @default.
- NCIT_C1196 NCIT_P322 "FDA" @default.
- NCIT_C1196 NCIT_P329 "40356" @default.
- NCIT_C1196 NCIT_P330 "40356" @default.
- NCIT_C1196 NCIT_P350 "C11H18N4O3" @default.
- NCIT_C1196 NCIT_P366 "Pimonidazole" @default.
- NCIT_C1196 NCIT_P399 "40356" @default.
- NCIT_C1196 normalizedInformationContent "100" @default.
- NCIT_C1196 referenceCount "1" @default.
- NCIT_C1196 hasExactSynonym "1-piperidineethanol, alpha-((2-nitro-1h-imidazol-1-yl)methyl)-" @default.
- NCIT_C1196 hasExactSynonym "PD 126675" @default.
- NCIT_C1196 hasExactSynonym "PIMONIDAZOLE" @default.
- NCIT_C1196 hasExactSynonym "Pimonidazole" @default.
- NCIT_C1196 hasExactSynonym "Ro 03-8799" @default.
- NCIT_C1196 inSubset NCIT_C176424 @default.
- NCIT_C1196 inSubset NCIT_C63923 @default.
- NCIT_C1196 type Class @default.
- NCIT_C1196 isDefinedBy ncit.owl @default.
- NCIT_C1196 label "Pimonidazole" @default.
- NCIT_C1196 subClassOf NCIT_C1196 @default.
- NCIT_C1196 subClassOf NCIT_C1908 @default.
- NCIT_C1196 subClassOf NCIT_C1909 @default.
- NCIT_C1196 subClassOf NCIT_C274 @default.
- NCIT_C1196 subClassOf NCIT_C798 @default.