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- NCIT_C119703 IAO_0000115 "A preparation of autologous tumor infiltrating lymphocytes (TILs) expressing the co-stimulatory signaling domain 4-1BB (CD137), with potential antineoplastic activity. TILs are isolated from a patient's tumor and those expressing 4-1BB are selected for expansion in vitro. Upon re-infusion into the patient, the 4-1BB-expressing TILs re-infiltrate the tumor to initiate tumor cell lysis. 4-1BB, a member of the tumor necrosis factor (TNF) receptor superfamily, enhances TIL survival and antitumor cytolytic activity." @default.
- NCIT_C119703 NCIT_A7 NCIT_C105113 @default.
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- NCIT_C119703 NCIT_P106 "Cell" @default.
- NCIT_C119703 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C119703 NCIT_P107 "Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes" @default.
- NCIT_C119703 NCIT_P108 "Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes" @default.
- NCIT_C119703 NCIT_P207 "C3900007" @default.
- NCIT_C119703 NCIT_P322 "CTRP" @default.
- NCIT_C119703 NCIT_P399 "810763" @default.
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- NCIT_C119703 referenceCount "1" @default.
- NCIT_C119703 hasExactSynonym "Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes" @default.
- NCIT_C119703 hasExactSynonym "Autologous 4-1BB selected TILs" @default.
- NCIT_C119703 inSubset NCIT_C116977 @default.
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- NCIT_C119703 inSubset NCIT_C128784 @default.
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- NCIT_C119703 type Class @default.
- NCIT_C119703 isDefinedBy ncit.owl @default.
- NCIT_C119703 label "Autologous 4-1BB Selected Tumor Infiltrating Lymphocytes" @default.
- NCIT_C119703 subClassOf NCIT_C119703 @default.
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