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- NCIT_C119742 IAO_0000115 "A radioconjugate composed of the essential amino acid valine radiolabeled to carbon C 13 and nitrogen N 15, that can potentially be used as a tracer for protein metabolism in vivo using mass spectrometry (MS). Upon administration of carbon C 13/nitrogen N 15-labeled valine, the exogenous valine is taken up by cells and incorporated into proteins. Upon imaging, protein biomarkers containing radiolabeled valine are secreted by tumor cells and can be identified by MS. This may aid in cancer diagnosis and prognosis. Compared to normal cells, tumor cells rapidly take up amino acids to use as protein building blocks." @default.
- NCIT_C119742 NCIT_NHC0 "C119742" @default.
- NCIT_C119742 NCIT_P106 "Indicator, Reagent, or Diagnostic Aid" @default.
- NCIT_C119742 NCIT_P106 "Organic Chemical" @default.
- NCIT_C119742 NCIT_P108 "Carbon C 13/Nitrogen N 15-labeled Valine" @default.
- NCIT_C119742 NCIT_P207 "C3899707" @default.
- NCIT_C119742 NCIT_P210 "202407-30-5" @default.
- NCIT_C119742 NCIT_P329 "767080" @default.
- NCIT_C119742 NCIT_P330 "767080" @default.
- NCIT_C119742 NCIT_P399 "767080" @default.
- NCIT_C119742 normalizedInformationContent "100" @default.
- NCIT_C119742 referenceCount "1" @default.
- NCIT_C119742 hasExactSynonym "(+)-2-Amino-3-Methylbutyric Acid-13C5,15N" @default.
- NCIT_C119742 hasExactSynonym "C13 N15 Valine" @default.
- NCIT_C119742 hasExactSynonym "Carbon C 13/Nitrogen N 15-labeled Valine" @default.
- NCIT_C119742 hasExactSynonym "Carbonomic" @default.
- NCIT_C119742 hasExactSynonym "L-2-Amino-3-methylbutanoic Acid-13C5,15N" @default.
- NCIT_C119742 hasExactSynonym "L-Valine-13C5,15N" @default.
- NCIT_C119742 inSubset NCIT_C176424 @default.
- NCIT_C119742 type Class @default.
- NCIT_C119742 isDefinedBy ncit.owl @default.
- NCIT_C119742 label "Carbon C 13/Nitrogen N 15-labeled Valine" @default.
- NCIT_C119742 subClassOf NCIT_C119742 @default.
- NCIT_C119742 subClassOf NCIT_C1446 @default.
- NCIT_C119742 subClassOf NCIT_C1908 @default.
- NCIT_C119742 subClassOf NCIT_C1909 @default.
- NCIT_C119742 subClassOf NCIT_C2124 @default.