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- NCIT_C119745 IAO_0000115 "A carbohydrate-based vaccine comprised of the Globo H hexasaccharide 1 (Globo H) antigen conjugated to DT-CRM197, a non-toxic, mutated form of diphtheria toxin (DT), with potential immunostimulating and antineoplastic activities. Upon administration of Globo H-DT vaccine OBI-833, the carbohydrate antigen Globo H may stimulate a cytotoxic T-lymphocyte (CTL) response against Globo H-expressing tumor cells, thereby decreasing tumor cell proliferation. The hexasaccharide Globo H is a tumor-associated antigen (TAA) commonly found on a variety of tumor cells. DT-CRM197, also called diphtheria toxin cross-reacting material 197, is used to increase the immunogenicity of the Globo H carbohydrate antigen." @default.
- NCIT_C119745 NCIT_A32 NCIT_C1909 @default.
- NCIT_C119745 NCIT_NHC0 "C119745" @default.
- NCIT_C119745 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C119745 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C119745 NCIT_P108 "Globo H-DT Vaccine OBI-833" @default.
- NCIT_C119745 NCIT_P207 "C3896801" @default.
- NCIT_C119745 NCIT_P210 "2142641-90-3" @default.
- NCIT_C119745 NCIT_P319 "NC1XBS5AET" @default.
- NCIT_C119745 NCIT_P322 "FDA" @default.
- NCIT_C119745 NCIT_P322 "GDC" @default.
- NCIT_C119745 NCIT_P329 "767196" @default.
- NCIT_C119745 NCIT_P330 "767196" @default.
- NCIT_C119745 NCIT_P375 "Globo H-DT Vaccine OBI-833" @default.
- NCIT_C119745 NCIT_P399 "767196" @default.
- NCIT_C119745 normalizedInformationContent "100" @default.
- NCIT_C119745 referenceCount "1" @default.
- NCIT_C119745 hasExactSynonym "Globo H-CRM197 Vaccine" @default.
- NCIT_C119745 hasExactSynonym "Globo H-DT Vaccine OBI-833" @default.
- NCIT_C119745 hasExactSynonym "OBI-833" @default.
- NCIT_C119745 inSubset NCIT_C128784 @default.
- NCIT_C119745 inSubset NCIT_C157711 @default.
- NCIT_C119745 inSubset NCIT_C157712 @default.
- NCIT_C119745 inSubset NCIT_C176424 @default.
- NCIT_C119745 inSubset NCIT_C177537 @default.
- NCIT_C119745 inSubset NCIT_C63923 @default.
- NCIT_C119745 type Class @default.
- NCIT_C119745 isDefinedBy ncit.owl @default.
- NCIT_C119745 label "Globo H-DT Vaccine OBI-833" @default.
- NCIT_C119745 subClassOf NCIT_C119745 @default.
- NCIT_C119745 subClassOf NCIT_C129820 @default.
- NCIT_C119745 subClassOf NCIT_C1455 @default.
- NCIT_C119745 subClassOf NCIT_C1663 @default.
- NCIT_C119745 subClassOf NCIT_C1908 @default.
- NCIT_C119745 subClassOf NCIT_C1909 @default.
- NCIT_C119745 subClassOf NCIT_C274 @default.
- NCIT_C119745 subClassOf NCIT_C307 @default.
- NCIT_C119745 subClassOf NCIT_C308 @default.
- NCIT_C119745 subClassOf NCIT_C923 @default.