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- NCIT_C120037 IAO_0000115 "An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, SERD SRN-927 specifically binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells." @default.
- NCIT_C120037 NCIT_A32 NCIT_C1909 @default.
- NCIT_C120037 NCIT_A7 NCIT_C38361 @default.
- NCIT_C120037 NCIT_NHC0 "C120037" @default.
- NCIT_C120037 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C120037 NCIT_P107 "Selective Estrogen Receptor Degrader SRN-927" @default.
- NCIT_C120037 NCIT_P108 "Selective Estrogen Receptor Degrader SRN-927" @default.
- NCIT_C120037 NCIT_P207 "C3896765" @default.
- NCIT_C120037 NCIT_P322 "CTRP" @default.
- NCIT_C120037 NCIT_P322 "GDC" @default.
- NCIT_C120037 NCIT_P329 "767384" @default.
- NCIT_C120037 NCIT_P330 "767384" @default.
- NCIT_C120037 NCIT_P375 "Selective Estrogen Receptor Degrader SRN-927" @default.
- NCIT_C120037 NCIT_P399 "767384" @default.
- NCIT_C120037 normalizedInformationContent "100" @default.
- NCIT_C120037 referenceCount "1" @default.
- NCIT_C120037 hasExactSynonym "SERD SRN-927" @default.
- NCIT_C120037 hasExactSynonym "SRN-927" @default.
- NCIT_C120037 hasExactSynonym "Selective Estrogen Receptor Degrader SRN-927" @default.
- NCIT_C120037 inSubset NCIT_C116977 @default.
- NCIT_C120037 inSubset NCIT_C116978 @default.
- NCIT_C120037 inSubset NCIT_C128784 @default.
- NCIT_C120037 inSubset NCIT_C157711 @default.
- NCIT_C120037 inSubset NCIT_C157712 @default.
- NCIT_C120037 inSubset NCIT_C176424 @default.
- NCIT_C120037 inSubset NCIT_C177537 @default.
- NCIT_C120037 type Class @default.
- NCIT_C120037 isDefinedBy ncit.owl @default.
- NCIT_C120037 label "Selective Estrogen Receptor Degrader SRN-927" @default.
- NCIT_C120037 subClassOf NCIT_C120037 @default.
- NCIT_C120037 subClassOf NCIT_C129818 @default.
- NCIT_C120037 subClassOf NCIT_C147908 @default.
- NCIT_C120037 subClassOf NCIT_C163758 @default.
- NCIT_C120037 subClassOf NCIT_C1908 @default.
- NCIT_C120037 subClassOf NCIT_C1909 @default.
- NCIT_C120037 subClassOf NCIT_C2116 @default.
- NCIT_C120037 subClassOf NCIT_C274 @default.
- NCIT_C120037 subClassOf NCIT_C481 @default.
- NCIT_C120037 subClassOf NCIT_C547 @default.