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- NCIT_C120041 IAO_0000115 "An agonistic, humanized monoclonal antibody against receptor OX40 (CD134), with potential immunostimulatory activity. Upon administration, tavolimab selectively binds to and activates the OX40 receptor. OX40 receptor activation induces proliferation of memory and effector T-lymphocytes. In the presence of tumor-associated antigens (TAAs), this agent may promote an immune response against TAAs-expressing tumor cells. OX40, a cell surface glycoprotein and member of the tumor necrosis factor (TNF) receptor family, is expressed on T-lymphocytes and provides a co-stimulatory signal for the proliferation and survival of activated T-cells." @default.
- NCIT_C120041 NCIT_A32 NCIT_C1909 @default.
- NCIT_C120041 NCIT_A7 NCIT_C94790 @default.
- NCIT_C120041 NCIT_NHC0 "C120041" @default.
- NCIT_C120041 NCIT_P106 "Amino Acid, Peptide, or Protein" @default.
- NCIT_C120041 NCIT_P106 "Immunologic Factor" @default.
- NCIT_C120041 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C120041 NCIT_P107 "Tavolimab" @default.
- NCIT_C120041 NCIT_P108 "Tavolimab" @default.
- NCIT_C120041 NCIT_P207 "C3896818" @default.
- NCIT_C120041 NCIT_P210 "1635395-25-3" @default.
- NCIT_C120041 NCIT_P319 "4LU9B48U4D" @default.
- NCIT_C120041 NCIT_P322 "CTRP" @default.
- NCIT_C120041 NCIT_P322 "FDA" @default.
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- NCIT_C120041 NCIT_P329 "767471" @default.
- NCIT_C120041 NCIT_P330 "767471" @default.
- NCIT_C120041 NCIT_P375 "Tavolimab" @default.
- NCIT_C120041 NCIT_P399 "767471" @default.
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- NCIT_C120041 NCIT_R72 NCIT_C12508 @default.
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- NCIT_C120041 NCIT_R72 NCIT_C33061 @default.
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- NCIT_C120041 NCIT_R72 NCIT_C39567 @default.
- NCIT_C120041 NCIT_R72 NCIT_C39568 @default.
- NCIT_C120041 normalizedInformationContent "100" @default.
- NCIT_C120041 referenceCount "1" @default.
- NCIT_C120041 hasExactSynonym "Anti-OX40 Monoclonal Antibody MEDI0562" @default.
- NCIT_C120041 hasExactSynonym "MEDI-0562" @default.
- NCIT_C120041 hasExactSynonym "MEDI0562" @default.
- NCIT_C120041 hasExactSynonym "TAVOLIMAB" @default.
- NCIT_C120041 hasExactSynonym "Tavolimab" @default.
- NCIT_C120041 hasExactSynonym "Tavolixizumab" @default.
- NCIT_C120041 inSubset NCIT_C116977 @default.
- NCIT_C120041 inSubset NCIT_C116978 @default.
- NCIT_C120041 inSubset NCIT_C128784 @default.
- NCIT_C120041 inSubset NCIT_C157711 @default.
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- NCIT_C120041 type Class @default.
- NCIT_C120041 isDefinedBy ncit.owl @default.
- NCIT_C120041 label "Tavolimab" @default.
- NCIT_C120041 subClassOf B36f84bf5f52a03285da9bfdebb4410fe @default.
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- NCIT_C120041 subClassOf NCIT_C307 @default.
- NCIT_C120041 subClassOf NCIT_C308 @default.
- NCIT_C120041 subClassOf NCIT_C96040 @default.