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- NCIT_C120063 IAO_0000115 "A mutation in the region of the FLT3 gene that encodes the second tyrosine kinase domain of the receptor-type tyrosine-protein kinase FLT3 that causes the stabilization of the activation loop of the kinase domain. FLT3 activation loop mutations lead to constitutive tyrosine kinase activity and are associated with acute myeloid leukemia." @default.
- NCIT_C120063 NCIT_NHC0 "C120063" @default.
- NCIT_C120063 NCIT_P106 "Cell or Molecular Dysfunction" @default.
- NCIT_C120063 NCIT_P107 "FLT3 Activation Loop Mutation" @default.
- NCIT_C120063 NCIT_P108 "FLT3 Activation Loop Mutation" @default.
- NCIT_C120063 NCIT_P207 "C3899165" @default.
- NCIT_C120063 NCIT_P322 "CTRP" @default.
- NCIT_C120063 NCIT_P98 "The majority of FLT3 activation loop mutations involve the deletion of or point mutations in codon 835 (aspartate 835) or point mutations in codon 836 (isoleucine 836)." @default.
- NCIT_C120063 NCIT_R177 NCIT_C16612 @default.
- NCIT_C120063 NCIT_R177 NCIT_C20103 @default.
- NCIT_C120063 NCIT_R177 NCIT_C20719 @default.
- NCIT_C120063 NCIT_R177 NCIT_C21281 @default.
- NCIT_C120063 NCIT_R177 NCIT_C21295 @default.
- NCIT_C120063 NCIT_R177 NCIT_C24399 @default.
- NCIT_C120063 NCIT_R177 NCIT_C25870 @default.
- NCIT_C120063 NCIT_R177 NCIT_C25871 @default.
- NCIT_C120063 NCIT_R177 NCIT_C25872 @default.
- NCIT_C120063 NCIT_R177 NCIT_C26131 @default.
- NCIT_C120063 NCIT_R178 NCIT_C128920 @default.
- NCIT_C120063 NCIT_R178 NCIT_C3910 @default.
- NCIT_C120063 NCIT_R178 NCIT_C97926 @default.
- NCIT_C120063 NCIT_R178 NCIT_C97928 @default.
- NCIT_C120063 normalizedInformationContent "90.826665450122817" @default.
- NCIT_C120063 referenceCount "4" @default.
- NCIT_C120063 hasExactSynonym "FLT3 A-Loop Mutation" @default.
- NCIT_C120063 hasExactSynonym "FLT3 Activation Loop Mutation" @default.
- NCIT_C120063 hasExactSynonym "FLT3 Tyrosine Kinase Domain Mutation" @default.
- NCIT_C120063 hasExactSynonym "FLT3- TKD mutations" @default.
- NCIT_C120063 hasExactSynonym "FLT3-ALM" @default.
- NCIT_C120063 hasExactSynonym "FLT3-TKD Mutation" @default.
- NCIT_C120063 hasExactSynonym "FLT3/TKD Mutation" @default.
- NCIT_C120063 inSubset NCIT_C116977 @default.
- NCIT_C120063 inSubset NCIT_C142799 @default.
- NCIT_C120063 inSubset NCIT_C142800 @default.
- NCIT_C120063 type Class @default.
- NCIT_C120063 isDefinedBy ncit.owl @default.
- NCIT_C120063 label "FLT3 Activation Loop Mutation" @default.
- NCIT_C120063 subClassOf B97fbf4851a652490ab1b9d3b65ada33f @default.
- NCIT_C120063 subClassOf Beb9c394004137035b3a5c2d29b83cf3d @default.
- NCIT_C120063 subClassOf NCIT_C120063 @default.
- NCIT_C120063 subClassOf NCIT_C128919 @default.
- NCIT_C120063 subClassOf NCIT_C141240 @default.
- NCIT_C120063 subClassOf NCIT_C150623 @default.
- NCIT_C120063 subClassOf NCIT_C178120 @default.
- NCIT_C120063 subClassOf NCIT_C36327 @default.
- NCIT_C120063 subClassOf NCIT_C36391 @default.
- NCIT_C120063 subClassOf NCIT_C3910 @default.
- NCIT_C120063 subClassOf NCIT_C97926 @default.
- NCIT_C120063 subClassOf NCIT_C97927 @default.