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- NCIT_C120070 IAO_0000115 "A radioconjugate composed of an analog of the synthetic, alicyclic amino acid aminocyclopentane carboxylic acid (ACPC) radiolabeled with the positron-emitting isotope fluorine F 18 (2-[18F]FACPC), with potential cancer cell imaging activity during positron emission tomography (PET). As tumor cells have a higher rate of protein synthesis than normal, healthy cells, upon administration, fluorine F 18 labeled 2-FACPC is selectively taken up by rapidly proliferating tumor cells through the sodium-independent subtype L amino acid transport system (AAT) which leads to the accumulation of this tracer in tumor cells. Upon PET, tumor cells can then be visualized." @default.
- NCIT_C120070 NCIT_NHC0 "C120070" @default.
- NCIT_C120070 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C120070 NCIT_P107 "Fluorine F 18-labeled 2-FACPC" @default.
- NCIT_C120070 NCIT_P108 "Fluorine F 18-labeled 2-FACPC" @default.
- NCIT_C120070 NCIT_P207 "C3896948" @default.
- NCIT_C120070 NCIT_P322 "CTRP" @default.
- NCIT_C120070 normalizedInformationContent "100" @default.
- NCIT_C120070 referenceCount "1" @default.
- NCIT_C120070 hasExactSynonym "1-Amino-2-[18F]fluorocyclopentane-1-carboxylic Acid" @default.
- NCIT_C120070 hasExactSynonym "2-[(18)F]FACPC" @default.
- NCIT_C120070 hasExactSynonym "2-[18F]FACPC" @default.
- NCIT_C120070 hasExactSynonym "Anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic Acid" @default.
- NCIT_C120070 hasExactSynonym "Anti-2-[(18)F]FACPC" @default.
- NCIT_C120070 hasExactSynonym "Fluorine F 18-labeled 2-FACPC" @default.
- NCIT_C120070 inSubset NCIT_C116977 @default.
- NCIT_C120070 inSubset NCIT_C116978 @default.
- NCIT_C120070 type Class @default.
- NCIT_C120070 isDefinedBy ncit.owl @default.
- NCIT_C120070 label "Fluorine F 18-labeled 2-FACPC" @default.
- NCIT_C120070 subClassOf NCIT_C120070 @default.
- NCIT_C120070 subClassOf NCIT_C1446 @default.
- NCIT_C120070 subClassOf NCIT_C1908 @default.
- NCIT_C120070 subClassOf NCIT_C1909 @default.
- NCIT_C120070 subClassOf NCIT_C2124 @default.