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- NCIT_C1202 IAO_0000115 "The acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. As a glucocorticoid receptor agonist, prednisolone acetate binds to specific intracellular glucocorticoid receptors, and causes the ligand-receptor complex to be translocated to the nucleus where it initiates the transcription of glucocorticoid-responsive genes such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations." @default.
- NCIT_C1202 NCIT_A32 NCIT_C1909 @default.
- NCIT_C1202 NCIT_NHC0 "C1202" @default.
- NCIT_C1202 NCIT_P106 "Organic Chemical" @default.
- NCIT_C1202 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C1202 NCIT_P108 "Prednisolone Acetate" @default.
- NCIT_C1202 NCIT_P175 "10966" @default.
- NCIT_C1202 NCIT_P207 "C0071839" @default.
- NCIT_C1202 NCIT_P210 "52-21-1" @default.
- NCIT_C1202 NCIT_P319 "8B2807733D" @default.
- NCIT_C1202 NCIT_P322 "FDA" @default.
- NCIT_C1202 NCIT_P322 "GDC" @default.
- NCIT_C1202 NCIT_P350 "C23H30O6" @default.
- NCIT_C1202 NCIT_P366 "Prednisolone_Acetate" @default.
- NCIT_C1202 NCIT_P375 "Prednisolone Acetate" @default.
- NCIT_C1202 NCIT_R122 NCIT_C16484 @default.
- NCIT_C1202 NCIT_R122 NCIT_C16486 @default.
- NCIT_C1202 NCIT_R122 NCIT_C16554 @default.
- NCIT_C1202 NCIT_R122 NCIT_C16865 @default.
- NCIT_C1202 NCIT_R122 NCIT_C16946 @default.
- NCIT_C1202 NCIT_R122 NCIT_C17021 @default.
- NCIT_C1202 NCIT_R122 NCIT_C17573 @default.
- NCIT_C1202 NCIT_R122 NCIT_C20027 @default.
- NCIT_C1202 NCIT_R122 NCIT_C26548 @default.
- NCIT_C1202 NCIT_R122 NCIT_C28459 @default.
- NCIT_C1202 normalizedInformationContent "92.730304365937428" @default.
- NCIT_C1202 referenceCount "3" @default.
- NCIT_C1202 hasExactSynonym "Ak-Tate" @default.
- NCIT_C1202 hasExactSynonym "Articulose-50" @default.
- NCIT_C1202 hasExactSynonym "Balpred" @default.
- NCIT_C1202 hasExactSynonym "Deltacortilen" @default.
- NCIT_C1202 hasExactSynonym "Deltastab" @default.
- NCIT_C1202 hasExactSynonym "Di-Adreson-F" @default.
- NCIT_C1202 hasExactSynonym "Diopred" @default.
- NCIT_C1202 hasExactSynonym "Econopred" @default.
- NCIT_C1202 hasExactSynonym "Flo-Pred" @default.
- NCIT_C1202 hasExactSynonym "Hexacortone" @default.
- NCIT_C1202 hasExactSynonym "Hydrocortancyl" @default.
- NCIT_C1202 hasExactSynonym "Inf-Oph" @default.
- NCIT_C1202 hasExactSynonym "Inflanefran" @default.
- NCIT_C1202 hasExactSynonym "Key-Pred" @default.
- NCIT_C1202 hasExactSynonym "Locaseptil-Neo" @default.
- NCIT_C1202 hasExactSynonym "Ophtho-Tate" @default.
- NCIT_C1202 hasExactSynonym "PREDNISOLONE ACETATE" @default.
- NCIT_C1202 hasExactSynonym "Pred Fort" @default.
- NCIT_C1202 hasExactSynonym "Pred Forte" @default.
- NCIT_C1202 hasExactSynonym "Pred Mild" @default.
- NCIT_C1202 hasExactSynonym "Predaject" @default.
- NCIT_C1202 hasExactSynonym "Predalone" @default.
- NCIT_C1202 hasExactSynonym "Predate" @default.
- NCIT_C1202 hasExactSynonym "Predcor" @default.
- NCIT_C1202 hasExactSynonym "Prednefrin SF" @default.
- NCIT_C1202 hasExactSynonym "Predni-H" @default.
- NCIT_C1202 hasExactSynonym "Predni-POS" @default.
- NCIT_C1202 hasExactSynonym "Prednihexal" @default.
- NCIT_C1202 hasExactSynonym "Predniocil" @default.
- NCIT_C1202 hasExactSynonym "Prednisolone Acetate" @default.
- NCIT_C1202 hasExactSynonym "Prednisolone acetate" @default.
- NCIT_C1202 inSubset NCIT_C157711 @default.
- NCIT_C1202 inSubset NCIT_C157712 @default.
- NCIT_C1202 inSubset NCIT_C173381 @default.
- NCIT_C1202 inSubset NCIT_C173383 @default.
- NCIT_C1202 inSubset NCIT_C177537 @default.
- NCIT_C1202 inSubset NCIT_C63923 @default.
- NCIT_C1202 type Class @default.
- NCIT_C1202 isDefinedBy ncit.owl @default.
- NCIT_C1202 label "Prednisolone Acetate" @default.
- NCIT_C1202 subClassOf NCIT_C1202 @default.
- NCIT_C1202 subClassOf NCIT_C147908 @default.
- NCIT_C1202 subClassOf NCIT_C1636 @default.
- NCIT_C1202 subClassOf NCIT_C1908 @default.
- NCIT_C1202 subClassOf NCIT_C1909 @default.
- NCIT_C1202 subClassOf NCIT_C211 @default.
- NCIT_C1202 subClassOf NCIT_C2364 @default.
- NCIT_C1202 subClassOf NCIT_C308 @default.
- NCIT_C1202 subClassOf NCIT_C521 @default.
- NCIT_C1202 subClassOf NCIT_C548 @default.
- NCIT_C1202 subClassOf NCIT_C574 @default.