Matches in Ubergraph for { <http://purl.obolibrary.org/obo/NCIT_C120311> ?p ?o ?g. }
Showing items 1 to 36 of
36
with 100 items per page.
- NCIT_C120311 IAO_0000115 "A radioconjugate composed of the positron-emitting radioisotope fluorine F 18 labeled benzylguanidine, a synthetic analogue of the adrenergic neurotransmitter norepinephrine (NE), with potential use in the diagnostic imaging of human norepinephrine transporter (hNET)-expressing cells by either positron emitting tomography (PET) or computed tomography (CT). Upon administration, meta-fluorine F 18 fluorobenzylguanidine (MFBG) is taken up by and accumulates in both the granules of adrenal medullary chromaffin cells and the pre-synaptic granules of adrenergic neurons in a manner almost identical to that of NE. In turn, hNET-expressing tumor cells can be imaged by PET or CT. hNET, a transmembrane protein and regulator of catecholamine uptake normally restricted to the central and peripheral sympathetic nervous system, is overexpressed in certain tumor cell types." @default.
- NCIT_C120311 NCIT_A7 NCIT_C117244 @default.
- NCIT_C120311 NCIT_NHC0 "C120311" @default.
- NCIT_C120311 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C120311 NCIT_P107 "meta-Fluorine F 18 Fluorobenzylguanidine" @default.
- NCIT_C120311 NCIT_P108 "meta-Fluorine F 18 Fluorobenzylguanidine" @default.
- NCIT_C120311 NCIT_P207 "C0665292" @default.
- NCIT_C120311 NCIT_P210 "156021-12-4" @default.
- NCIT_C120311 NCIT_P319 "CD7WXM716P" @default.
- NCIT_C120311 NCIT_P322 "CTRP" @default.
- NCIT_C120311 NCIT_P322 "FDA" @default.
- NCIT_C120311 NCIT_P329 "768769" @default.
- NCIT_C120311 NCIT_P330 "768769" @default.
- NCIT_C120311 NCIT_P399 "768769" @default.
- NCIT_C120311 normalizedInformationContent "100" @default.
- NCIT_C120311 referenceCount "1" @default.
- NCIT_C120311 hasExactSynonym "18F meta-Fluoro Benzylguanidine" @default.
- NCIT_C120311 hasExactSynonym "18F-MFBG" @default.
- NCIT_C120311 hasExactSynonym "IRP 101" @default.
- NCIT_C120311 hasExactSynonym "M-(18F)-FLUOROBENZYLGUANIDINE" @default.
- NCIT_C120311 hasExactSynonym "Meta-fluoro Benzylguanidine F-18" @default.
- NCIT_C120311 hasExactSynonym "[(18)F]-MFBG" @default.
- NCIT_C120311 hasExactSynonym "meta-Fluorine F 18 Fluorobenzylguanidine" @default.
- NCIT_C120311 hasExactSynonym "meta-[(18)F]-Fluorobenzylguanidine" @default.
- NCIT_C120311 inSubset NCIT_C116977 @default.
- NCIT_C120311 inSubset NCIT_C116978 @default.
- NCIT_C120311 inSubset NCIT_C176424 @default.
- NCIT_C120311 inSubset NCIT_C63923 @default.
- NCIT_C120311 type Class @default.
- NCIT_C120311 isDefinedBy ncit.owl @default.
- NCIT_C120311 label "meta-Fluorine F 18 Fluorobenzylguanidine" @default.
- NCIT_C120311 subClassOf NCIT_C120311 @default.
- NCIT_C120311 subClassOf NCIT_C1446 @default.
- NCIT_C120311 subClassOf NCIT_C1908 @default.
- NCIT_C120311 subClassOf NCIT_C1909 @default.
- NCIT_C120311 subClassOf NCIT_C2124 @default.