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- NCIT_C120315 IAO_0000115 "A formulation for intravenous injection containing ibuprofen, a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous injection, ibuprofen inhibits the activity of the enzymes cyclooxygenase I (COX-1) and II (COX-2), resulting in a decreased formation of precursors of prostaglandins and thromboxanes. Inhibition of COX-2 specifically blocks the conversion of arachidonic acid (AA) to prostaglandins, which mediate inflammation, fever and pain." @default.
- NCIT_C120315 NCIT_NHC0 "C120315" @default.
- NCIT_C120315 NCIT_P106 "Organic Chemical" @default.
- NCIT_C120315 NCIT_P106 "Pharmacologic Substance" @default.
- NCIT_C120315 NCIT_P108 "Ibuprofen Injection" @default.
- NCIT_C120315 NCIT_P207 "C2702462" @default.
- NCIT_C120315 NCIT_P329 "768805" @default.
- NCIT_C120315 NCIT_P330 "768805" @default.
- NCIT_C120315 NCIT_P399 "768805" @default.
- NCIT_C120315 NCIT_R124 NCIT_C17710 @default.
- NCIT_C120315 NCIT_R124 NCIT_C17828 @default.
- NCIT_C120315 NCIT_R124 NCIT_C28498 @default.
- NCIT_C120315 NCIT_R124 NCIT_C40576 @default.
- NCIT_C120315 NCIT_R124 NCIT_C40577 @default.
- NCIT_C120315 normalizedInformationContent "100" @default.
- NCIT_C120315 referenceCount "1" @default.
- NCIT_C120315 hasExactSynonym "Caldolor" @default.
- NCIT_C120315 hasExactSynonym "Ibuprofen Injection" @default.
- NCIT_C120315 inSubset NCIT_C176424 @default.
- NCIT_C120315 type Class @default.
- NCIT_C120315 isDefinedBy ncit.owl @default.
- NCIT_C120315 label "Ibuprofen Injection" @default.
- NCIT_C120315 subClassOf B730b28bf1945b727dc3db30500639dae @default.
- NCIT_C120315 subClassOf B8eb0c753b7e485f7b6622010dd4f430a @default.
- NCIT_C120315 subClassOf NCIT_C120315 @default.
- NCIT_C120315 subClassOf NCIT_C1323 @default.
- NCIT_C120315 subClassOf NCIT_C1908 @default.
- NCIT_C120315 subClassOf NCIT_C1909 @default.
- NCIT_C120315 subClassOf NCIT_C2198 @default.
- NCIT_C120315 subClassOf NCIT_C2356 @default.
- NCIT_C120315 subClassOf NCIT_C241 @default.
- NCIT_C120315 subClassOf NCIT_C257 @default.
- NCIT_C120315 subClassOf NCIT_C471 @default.
- NCIT_C120315 subClassOf NCIT_C78272 @default.