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- NCIT_C120469 IAO_0000115 "An endogenous metabolite formed during the O-methylation of the highly carcinogenic catechol estrogen 4-hydroxyestradiol (4-OHE2) by catechol-O-methyltransferase (COMT), with potential anti-proliferative activity. Even though the exact mechanism of action through which 4-methoxyestradiol (4-MeE2) exerts its effect is not fully elucidated, this chemical appears to have antiproliferative and apoptosis-inducing activities in susceptible tumor cells." @default.
- NCIT_C120469 NCIT_NHC0 "C120469" @default.
- NCIT_C120469 NCIT_P106 "Organic Chemical" @default.
- NCIT_C120469 NCIT_P107 "4-Methoxyestradiol" @default.
- NCIT_C120469 NCIT_P108 "4-Methoxyestradiol" @default.
- NCIT_C120469 NCIT_P207 "C0048460" @default.
- NCIT_C120469 NCIT_P210 "26788-23-8" @default.
- NCIT_C120469 NCIT_P322 "CTRP" @default.
- NCIT_C120469 normalizedInformationContent "100" @default.
- NCIT_C120469 referenceCount "1" @default.
- NCIT_C120469 hasExactSynonym "4-MeE2" @default.
- NCIT_C120469 hasExactSynonym "4-MeOE2" @default.
- NCIT_C120469 hasExactSynonym "4-Methoxyestradiol" @default.
- NCIT_C120469 hasExactSynonym "4-Methoxyestradiol-17 Beta" @default.
- NCIT_C120469 hasExactSynonym "4-Methoxyestradiol-17beta" @default.
- NCIT_C120469 hasExactSynonym "Estra-1,3,5(10)-Triene-3,17-Diol, 4-Methoxy-, (17beta)-" @default.
- NCIT_C120469 inSubset NCIT_C116977 @default.
- NCIT_C120469 inSubset NCIT_C142799 @default.
- NCIT_C120469 type Class @default.
- NCIT_C120469 isDefinedBy ncit.owl @default.
- NCIT_C120469 label "4-Methoxyestradiol" @default.
- NCIT_C120469 subClassOf NCIT_C120469 @default.
- NCIT_C120469 subClassOf NCIT_C147908 @default.
- NCIT_C120469 subClassOf NCIT_C1636 @default.
- NCIT_C120469 subClassOf NCIT_C1908 @default.
- NCIT_C120469 subClassOf NCIT_C1909 @default.
- NCIT_C120469 subClassOf NCIT_C2181 @default.
- NCIT_C120469 subClassOf NCIT_C483 @default.
- NCIT_C120469 subClassOf NCIT_C548 @default.